Protein Info for mRNA_1904 in Rhodosporidium toruloides IFO0880

Name: 10272
Annotation: HMMPfam-Protein kinase domain-PF00069,ProSitePatterns-Serine/Threonine protein kinases active-site signature.-PS00108,ProSiteProfiles-Protein kinase domain profile.-PS50011,SMART-Serine/Threonine protein kinases, catalytic domain-SM00220,SUPERFAMILY--SSF56112

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 390 transmembrane" amino acids 67 to 86 (20 residues), see Phobius details amino acids 98 to 113 (16 residues), see Phobius details PF07714: Pkinase_Tyr" amino acids 30 to 230 (201 residues), 71.3 bits, see alignment E=1.6e-23 PF00069: Pkinase" amino acids 30 to 310 (281 residues), 187 bits, see alignment E=9.1e-59 PF06293: Kdo" amino acids 121 to 173 (53 residues), 25.1 bits, see alignment 2.1e-09 PF01636: APH" amino acids 143 to 176 (34 residues), 27.1 bits, see alignment 8e-10

Best Hits

KEGG orthology group: K00924, [EC: 2.7.1.-] (inferred from 54% identity to ang:ANI_1_32134)

Predicted SEED Role

"Low-specificity L-threonine aldolase (EC 4.1.2.48)" (EC 4.1.2.48)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.-, 4.1.2.48

Use Curated BLAST to search for 2.7.1.- or 4.1.2.48

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (390 amino acids)

>mRNA_1904 HMMPfam-Protein kinase domain-PF00069,ProSitePatterns-Serine/Threonine protein kinases active-site signature.-PS00108,ProSiteProfiles-Protein kinase domain profile.-PS50011,SMART-Serine/Threonine protein kinases, catalytic domain-SM00220,SUPERFAMILY--SSF56112 (Rhodosporidium toruloides IFO0880)
IDDTRVYRVVATDASNNKQVELAFVHTAAAGHGSFGVVFRGELVRGGHGVVAFKRTRQDK
RFKNRELQIMSAVSHPNIVMMLFYWYESAQDEGDSIVVLNLVLEFLPETLYRAYRTYTKR
RQYFPEISTKLYMYQLLRALAYLHAVGVCHRDVKPHNVLVDADSGRLVLIDFGSAKVLRE
GVENVSYACSRYYRAPELIFGSTRYNDSIDVWSAGCVLGELLCGSVFFPGESSIDQLVEI
VKVLGTPTREHVKAMNAHYTEHNFPQVQAVPLEQVSFEVACSAIDLLGSLILYDPSRRLT
AIEAMAHHFFDDLRRGNMRESNGSWGVQMPNGKCVTVGLFDFSKFELSIRPDLNTILVPP
HARQALLIEQDVDLETFIPLDLDAHRLNLD