Protein Info for mRNA_1940 in Rhodosporidium toruloides IFO0880
Name: 10308
Annotation: K00276 AOC3, AOC2, tynA primary-amine oxidase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00276, primary-amine oxidase [EC: 1.4.3.21] (inferred from 44% identity to ang:ANI_1_80034)Predicted SEED Role
"Monoamine oxidase (1.4.3.4)" in subsystem Aromatic Amin Catabolism or Auxin biosynthesis or Glycine and Serine Utilization or Threonine degradation
MetaCyc Pathways
- phenylethylamine degradation I (2/2 steps found)
- salidroside biosynthesis (3/4 steps found)
- L-threonine degradation III (to methylglyoxal) (2/3 steps found)
- phenylethanol biosynthesis (3/5 steps found)
- superpathway of L-threonine metabolism (11/18 steps found)
- superpathway of phenylethylamine degradation (5/11 steps found)
- aromatic biogenic amine degradation (bacteria) (2/8 steps found)
KEGG Metabolic Maps
- Alkaloid biosynthesis I
- Alkaloid biosynthesis II
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Glycine, serine and threonine metabolism
- Phenylalanine metabolism
- Tyrosine metabolism
- beta-Alanine metabolism
Isozymes
Compare fitness of predicted isozymes for: 1.4.3.21
Use Curated BLAST to search for 1.4.3.21
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (714 amino acids)
>mRNA_1940 K00276 AOC3, AOC2, tynA primary-amine oxidase (Rhodosporidium toruloides IFO0880) MPVAVPIASHTTVPLKPKSSAPRSNPPHPLSTLQPDELRVAARVVKEYNSTKECLFRRIL LIEPPKKEVVPYLEAELAGKALPKPPIRRAQALFYFAGETEFMEATVDMTNARLLGQRHL EGEHGPGDDEEVLKIAEISLESPMVKKELERLQLPEGSEVIAEPWPYGSDETETPTRLSQ VWFFLNYKENKDHPSANFYAHPLDFSCVVEISKMEVIRIDRLPTDTNMTSESPDARYVPN KDCEYAPDLIEGGVRKDLKPLHIVQPEGVSFTIADDGETINWQKWSFKCCFDVREGMILR NVCYDGRPVFYRMALSEMTVPYGDPRAPLHRKSAFDLGECGAGQTANNLQLGCDCLGVIA YLDGMSCSHDGEPVKIPNAICIHEQDAGLGSKHTNIRTGRADVTRTRELVFQLIVTVGNY EYALYWIFDTAAAIHYEIRATGIMSVTPADASADVSTLGYGNLVAKGVFAPHHQHIFNLR IDPAMDDYRSNAVTYEDTTAMPRDPQTNPHGVGFVAKSTQVQQESAFNLDWTTNRFVKMV NPNKRNRFTNKPIGYKVVAPPTQLGLADPTSMHYIRGEFTDHHIHVTKYADDELWGSGEH LWQSRGGKGGCRTWASRGRELEGDSVLWFTLGFTHITRPEDWPVMPSEVFRMHFKPVGFF DQNPALDVPPSIQSINKSQYAFPNGNSSPPAPATNGVNGHAKTNGSTNGSCCGK