Protein Info for mRNA_2006 in Rhodosporidium toruloides IFO0880
Name: 10374
Annotation: K00380 cysJ sulfite reductase (NADPH) flavoprotein alpha-component
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2)" in subsystem Cysteine Biosynthesis (EC 1.8.1.2)
MetaCyc Pathways
- superpathway of L-methionine biosynthesis (by sulfhydrylation) (12/12 steps found)
- superpathway of sulfur amino acid biosynthesis (Saccharomyces cerevisiae) (9/10 steps found)
- assimilatory sulfate reduction I (4/4 steps found)
- assimilatory sulfate reduction III (3/3 steps found)
- superpathway of sulfate assimilation and cysteine biosynthesis (7/9 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.8.1.2
Use Curated BLAST to search for 1.8.1.2
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (1427 amino acids)
>mRNA_2006 K00380 cysJ sulfite reductase (NADPH) flavoprotein alpha-component (Rhodosporidium toruloides IFO0880) MAMASEGGGSACSLAARLGGHRETLFVNPRLTVLLPLPSVARNPHKMATLQTLHTLLEQD ALMSSSAVFTYDSTPSAPFGSTLPSRSTDARVYPMQVRAGAGSALVGFVESAAFTSKGAS EGKADKPVSVLAGSEAFLALVPSLLALPEQSKRPALNIHVSTQTSSLAPSHEAEGEPTLA QVPDLAAVLAGAKQLREGGWQGAVVFSETPEEAAVVGTALTKDAGKDLVNVFDGLTAGRQ LAPLSASSAVGAKNLDAALEAHQVPYFSYAGSSNASKVLVLPASTYSAAAKAAILASSTE DVGVLTVRVLQPWNSQALFAALPKSVKNLFVFTEEGEASGPLFEEVLESVLEQGDAKIKV RALPVKADSVPTVQDWAVRIAKIAGTKPAPLKSLLPAHAKLAVWWDLDSTSGSTESVPST LAHTFSAPNTGVSAKLQVTYDNFRQGGVQHAALLLEQAGKASTESTVASVVATTAPSLLY IGAPQSVFKAYGPISAQTVDKDTRVVVAGNWTAEDFATKLPYAQRKALVDIAAGSKGHVF SIDVDKVAKAHGVAASDVAEIVFWTLYLPASISAKELVALLAQTPTFVDWNAAKLVEVNG AVRNALVKVDVVPEWADEPVDDEGKKVDIPAALPPVLVPTAAGPNAFRTFADPAPGIAGG TSAQKHSWHHAAHRLLFPEAFSLDTTFENKLRPDLPEKNYLITVSENRRLTPDTYDRNVF HIEFSTAGTGLKYAVGEALGIHGWNDADEVREFLEWYGLDPEAVVNLPSRHDHSRVEQRT IFQVFQQNLDIFGKPGKSFYETLSKYATNKNEERALRFIASPEGSSTFKKMSELETVTYA DILRQFPSAKPTVEDLVREIEEIKPRHYSIASSQNFVGDSVHLLIVTVEWQTPKGSPRYG QCTRYLAGLKPGDKVMASIKPSVMKLPPLDTQPIVMAGLGTGAAPFRAFIQERAWQKAQG REVGPLVYYFGSRYRAQEYLYGEELEAYLQEGVLSHMGLAFSRDTDKKVYIQHKINEDGE LLAKLLEDDNGLFTLCGPTWPVPDVYEALVKALQTKGWSTEKAQARIEEMKEEERYSALF TRFFIVGGFAAGEAEGFGASLASPSFCFTSRLPPALRILAVSPPPRCATDIGLSTGIGGA PRCCRSVKESLVSPLPPYFLSSSSLAAHCPRRLFAMAQPTALSIQQQEYIGALDSSPKSS LPTLTFFSTAGEKRRYLADYIARHYPGAVPLSGHADEAAILQQAQCLCDLWLKELTQTTM RAMPEAQLAGDEVFIRRQRLAPDSQDEHIEIILPAMLAPVIHVGGSAHSMGIIRTGWAAQ GVGVHTWLRAQQDGVHLMACPALVYRASGNMQHLTDLGITAVRQWADGRLGGGSRWTLRS RNLPNKPNYTAMQDEQGSWQYEPYDAERYLKTPPTQAKWIRRDAHTQ