Protein Info for mRNA_2042 in Rhodosporidium toruloides IFO0880

Name: 10410
Annotation: K11228 STE11 mitogen-activated protein kinase kinase kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 299 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF00069: Pkinase" amino acids 6 to 267 (262 residues), 243.1 bits, see alignment E=5.4e-76 PF07714: Pkinase_Tyr" amino acids 7 to 263 (257 residues), 174.3 bits, see alignment E=4.6e-55

Best Hits

KEGG orthology group: K11228, mitogen-activated protein kinase kinase kinase [EC: 2.7.11.1] (inferred from 78% identity to lbc:LACBIDRAFT_229328)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.11.1

Use Curated BLAST to search for 2.7.11.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (299 amino acids)

>mRNA_2042 K11228 STE11 mitogen-activated protein kinase kinase kinase (Rhodosporidium toruloides IFO0880)
MKWIKGALIGAGSFGSVYLGMNPMTGSLMAVKQVELPTGKTHNEERKKGMLEALEREIEL
LKDLQHENIVQYLDSSMDGQHLNIFLEYVPGGSVAALLQNYGAFEEALVSKFVRQILTGL
DYLHEREIIHRDIKGANILVDNKGNIKISDFGISKKVEDTLLTGAKVHRPSLQGSVYWMA
PEVVKQTAYTSKADIWSLGCLVVEMLTGAHPWANLTQMQAIFRIGSSVRPTVPDDISSEA
DDFLEQTFEIEHTDRPSAKELLQHGFIRDPDAFAASQQTPTRATFSQNGSDNGSSSGGS