Protein Info for mRNA_2328 in Rhodosporidium toruloides IFO0880

Name: 10696
Annotation: KOG0192 Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 630 PF07714: Pkinase_Tyr" amino acids 1 to 139 (139 residues), 63.2 bits, see alignment E=3.6e-21 PF00069: Pkinase" amino acids 1 to 137 (137 residues), 86.2 bits, see alignment E=3.7e-28 PF00130: C1_1" amino acids 518 to 557 (40 residues), 31.5 bits, see alignment 2e-11

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (630 amino acids)

>mRNA_2328 KOG0192 Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs (Rhodosporidium toruloides IFO0880)
MHRDLKGENLLVTSNERLKICDFGLARVAPSGGAENEQWKRMTLCGTDGYMSPEILLGLP
FDLRTDIFSLGVLFVEIASRQLASQHQFARQLPDYGISTEEVWSSVSPNAPTSFVELALE
CCSTDPNKRPDAKAILRRLRDVEQEVAQLEAQGLGGADAHSRGGMGSMAANVGSVSFAGT
TKRGSVKHANGLGRGSTRPSAPRLPSFEGQINLRLGSSFVSSASDLPDLPSSYGPGQTAL
LHGHARTPSSAGQKDDEDDDEALLAIADADVPIDSLDMRPDSAYFANLRAAEAADDSTDY
STSVVKPSSRIVGSRIGGAGGPYGRLGSSSGSTLLVGDQNERGGSLPSLPPSWIAASEKS
SASLDGGEDEGAPTIIAPTPPRSKDDLDDPASFLTARTSTLSVAEAVVDGTAAQEDHDEE
RDVFHSTVQHMPAPAADLDVPYEAPHRFSLIRCVSEDDLLLDRLLKAWYFGRPGLQRFFG
SFAASPAASFADHSAGLGAANKRASWDAGSASPSQAGQGRCGQCEKKLGLMKAYLSCDDC
GLSVHIKCSDIIPPTCPASTSTAGTPTVLSPPLSPTSPSFPAHKPQKPTRPAPPPPSSAQ
DRPSKLVKKNRGGSGGAGGPSSSPLAALNT