Protein Info for mRNA_2341 in Rhodosporidium toruloides IFO0880

Name: 10709
Annotation: K03021 RPC2, POLR3B DNA-directed RNA polymerase III subunit RPC2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1174 transmembrane" amino acids 476 to 489 (14 residues), see Phobius details PF04563: RNA_pol_Rpb2_1" amino acids 50 to 439 (390 residues), 196.2 bits, see alignment E=1.7e-61 PF04561: RNA_pol_Rpb2_2" amino acids 198 to 397 (200 residues), 113.4 bits, see alignment E=3.7e-36 PF04565: RNA_pol_Rpb2_3" amino acids 476 to 539 (64 residues), 71.3 bits, see alignment 2.2e-23 PF04566: RNA_pol_Rpb2_4" amino acids 576 to 637 (62 residues), 87.9 bits, see alignment 1.5e-28 PF04567: RNA_pol_Rpb2_5" amino acids 658 to 698 (41 residues), 43.8 bits, see alignment (E = 1.1e-14) PF00562: RNA_pol_Rpb2_6" amino acids 705 to 1083 (379 residues), 421.7 bits, see alignment E=1.1e-129 PF04560: RNA_pol_Rpb2_7" amino acids 1085 to 1170 (86 residues), 113.2 bits, see alignment 2.1e-36

Best Hits

Predicted SEED Role

"DNA-directed RNA polymerase III second largest subunit (EC 2.7.7.6)" in subsystem RNA polymerase III (EC 2.7.7.6)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.6

Use Curated BLAST to search for 2.7.7.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1174 amino acids)

>mRNA_2341 K03021 RPC2, POLR3B DNA-directed RNA polymerase III subunit RPC2 (Rhodosporidium toruloides IFO0880)
MQDVGKDARHLVDGLEALGQDMYKGKSLSDPIKSVTDKWELLPAFLAVKGLVKQHIDSFN
YFVDVDLQAILRANARITSDVDPNFYLEYTDIRVGSPERPDENAINPSITPHECRLRDLS
YSAPVYVNIKYTRGKQEVVSKGIRIGRLPIMLRSNKCVLMGKNKAQLAQMNECPLDPGGY
FIVKGTEKVILVQEQLSKNRIIVETEPKKGLVQASVTSSTHERKSKTYVLTKHGKIYLKH
NSIHEDIPIGVVLRALGIVSAREIVQLVCGNDDDYRAAFGINIEEMDDLKTKSGQPIPVQ
TQQQALDYIGHRVKIIRKPAGTPGSGGAEKSWAPRRPASEEALEVLATVVLAHVPVEDLN
LRPKAIYIANMARRVLMAMLDPKNVDDRDYVGNKRLELAGQLLSLLFEDLFKKFNHDLKM
NIDKILKKSNRATEFDAIKQFQLHGDGITQGFVRAISTGNWSLKRFKMERAGITHVLSRL
SFISALGMMTRISSQFEKTRKVSGPRALQPSQWGMLCPSDTPEGEACGLVKNLALMTHIT
TDVEEEPIWNICFLIGVEDINVLDGTEIYAEGHLVVYLNGNVLGLTRCGPRFIRTFRHLR
RAGRINEFVSIYVNLQQQAIHIASDGGRICRPLIIVENGQSKVKELHMKMLREKVMTFDD
FLRKGLIEYLDVNEENDAYIALYENELKPETTHLEIEPFTLLGAVAGLIPYPHHNQSPRN
TYQCAMGKQAIGAIAHNQLNRIDTLLYLMVYPQTPMCRTRTIELIGYDQLPAGQNAMVAV
MSYSGYDIEDALILNRASVDRGFGRCQVFRKYTTLLKRYPNGMYDRLADPPKGENGEVLG
KYGILDLDGLAHVGEQVNPGQVYVNKQTPSNAHDNQLPGIDGPGGADAPASTWKNTGMSY
RAPIPGYIDKVLLTDTDSDSTLVKVLIRQTRRPELGDKFSSRHGQKGVCGLIVPQEDMPF
NDQGICPDVIMNPHGFPSRMTVGKMLELLSGKAGVLKGKFEYGTAFGGSKAEDMSRVLIE
HGYSYAGKDYLTSGITGQPLECYVYMGPIYYQKLKHMVLDKMHARARGPRAVLTRQPTEG
RSRDGGLRLGEMERDCLIAHGASQLLLERLMVSSDAFKVDVCGQCGFMGYNGWCKRCKTS
KAVVKLMIPYACKLLFQEMLAMGIAPRLKLEDAV