Protein Info for mRNA_2386 in Rhodosporidium toruloides IFO0880

Name: 10754
Annotation: K01530 E3.6.3.1 phospholipid-translocating ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1237 transmembrane" amino acids 212 to 231 (20 residues), see Phobius details amino acids 233 to 256 (24 residues), see Phobius details amino acids 480 to 499 (20 residues), see Phobius details amino acids 505 to 524 (20 residues), see Phobius details amino acids 1013 to 1033 (21 residues), see Phobius details amino acids 1039 to 1061 (23 residues), see Phobius details amino acids 1088 to 1105 (18 residues), see Phobius details amino acids 1119 to 1160 (42 residues), see Phobius details amino acids 1165 to 1187 (23 residues), see Phobius details amino acids 1200 to 1220 (21 residues), see Phobius details PF16209: PhoLip_ATPase_N" amino acids 175 to 232 (58 residues), 60.5 bits, see alignment 2.6e-20 TIGR01652: phospholipid-translocating P-type ATPase, flippase" amino acids 187 to 1235 (1049 residues), 1029.4 bits, see alignment E=0 PF00122: E1-E2_ATPase" amino acids 302 to 526 (225 residues), 54 bits, see alignment E=3.9e-18 TIGR01494: HAD ATPase, P-type, family IC" amino acids 457 to 598 (142 residues), 85.9 bits, see alignment E=2.1e-28 amino acids 923 to 1032 (110 residues), 96.4 bits, see alignment E=1.4e-31 PF00702: Hydrolase" amino acids 564 to 895 (332 residues), 39.9 bits, see alignment E=1.6e-13 PF13246: Cation_ATPase" amino acids 652 to 737 (86 residues), 33.3 bits, see alignment 1e-11 PF16212: PhoLip_ATPase_C" amino acids 979 to 1229 (251 residues), 166.2 bits, see alignment E=3e-52

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1237 amino acids)

>mRNA_2386 K01530 E3.6.3.1 phospholipid-translocating ATPase (Rhodosporidium toruloides IFO0880)
MAASSSRIAGRSGGQKSRLGTSRSQQGLHGAASSAGGSRATRGGRGTAGGSSYAGSSART
TLGTDLTDEDVQSEADVFSDRRRRRDGRVNGGQGYGKGRRIPPGLGGRGESEGEYDEGWS
TGLDIEEEEIRLLGQDEGPSARAPPSTSSRKRRLSVAQLLRLSSAPSSKPRTIPFNDAPS
KRKKSSFAPNLVKNQKYNVATFLPLVLYEQFKFFYNLYFLLVALSQFVPALRIGFLATYI
VPLAFVLAVTIGKEAFDDYKRYLRDRAANSALYSRLVPHSASTPHSHHASSSTPSSAPLK
PTPSSNLRVGDLVFLEKNDRVPADILLLRTSDPSGTCFVRTDQLDGETDWKLRVAVERTQ
ALQSDADLLEIEGDVYADPPTKDIHTFVGTLTVRSVPASRREAGADGADDAHQAEEEDDL
VAAHPVEPLTAENMLWANTVLAAGNAVGIVVYTGRETRAVMNTSQPGTKVGLLDHEINRL
AKILCAVTFALSVILVALNGFKGHWWVYVFRFLILFSSIIPISLRVNLDMGKTVYAHQIM
HDPEIPDTIVRTSTLPEELGRIEYLLSDKTGTLTQNEMELKKLHLGTMSYGIDSMDEVAH
QLATALGESKTNAGPQLATGVALATRGRRDMSSRVKDVALALGLCHNVTPVVDESDGSIT
YQASSPDEVAIVRFTESIGLTLSTRDRTSITLRTTAGATLSYEVLEIFPFTSESKRMGIV
VRDRQTGEIAFYQKGADVVMARIVAYNDWLEEECGNMAREGLRTLVMARKRLSEETWRDF
EEAYRDARVSLGDRNATCARVIADFLEHDLELLGVTGVEDKLQDDVKMTIELLRNAGIKI
WMLTGDKIETATCIAISTKLVSRGQYIHQIAKLKSPAQARDELEFLQSKLDCCLVIDGES
LQLCIEHFRQDFIELSTQLSAVVACRCSPTQKADVARLIRAHTKKRVCCIGDGGNDVSMI
QAADVGVGIVGKEGRQASLAADFSVNQFSYLTKLLVWHGRNSYKRSAKLAQFVIHRGLII
SVIQAVFSSVFYFSPIAIYQGWLMVGYATAYTMLPVFSLVLDRDVNEDVALLYPELYKEL
TKARGRSLSYKTFFTWLMISLYQGASHSPVSRSERPADALSFAGGAIMLLSLVLFESEFL
NIVSISFSALVVNELAMVAVEITTWHLAMVVSEVLTLALYVVSILFLPEYFDLSFVSSPT
FLSKVALIVAISVFPLFVIKYLKSKLAPTAYAKLRDF