Protein Info for mRNA_2389 in Rhodosporidium toruloides IFO0880

Name: 10757
Annotation: K10901 BLM, RECQL3, SGS1 bloom syndrome protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 821 TIGR00614: ATP-dependent DNA helicase, RecQ family" amino acids 172 to 636 (465 residues), 540.9 bits, see alignment E=1.3e-166 PF00270: DEAD" amino acids 185 to 356 (172 residues), 65.4 bits, see alignment E=1.2e-21 PF00271: Helicase_C" amino acids 393 to 500 (108 residues), 61.5 bits, see alignment E=1.9e-20 PF16124: RecQ_Zn_bind" amino acids 512 to 578 (67 residues), 64.1 bits, see alignment E=3.3e-21 PF09382: RQC" amino acids 583 to 697 (115 residues), 74.7 bits, see alignment E=1.1e-24

Best Hits

Predicted SEED Role

"ATP-dependent DNA helicase RecQ" in subsystem DNA-replication or DNA repair, bacterial RecFOR pathway

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (821 amino acids)

>mRNA_2389 K10901 BLM, RECQL3, SGS1 bloom syndrome protein (Rhodosporidium toruloides IFO0880)
MRFRPAGGAAAERSFEDNGSTFAGSANKRTHSTSTRFHPSANDDVSALLDGVDFDGDLDT
QEESLEIVESPAPRPPASRAKKPPSGLGLGVPAVRLDSPPPRYDPPQLRQQPARPPPPAA
QNRTVSAVSTASDLIIEEPRAAAASTSKAVAKAAPATKPKALHPWTKDVFKALRQRFGLK
SFRTNQEEAINATLAGRDVFVLLPTGGGKSLCFQLPAVVSTGVTSGVTIVVSPLLSLISD
QTRALYDKDIPVVFLNSTMPAADKKFVMSCLKNDPPMACLAYVTPEQIVKSKAFQNLLAD
LYNRKQLARFVIDEAHCVSSWGHDFRPDYKEMGSLKRDYPGIPLIALTATANGRVKQDVM
TNLRMDRPLMLTSSFNRANLKYFVRKKTRSVLSDIADFIKGEHAGESGIIYCSSKKQCED
TAERLRREHRIKCMHYHAGMDKDDRLRVQVQWLSGEIHVICATIAFGMGIDKPDVRFVCH
YTLSQSLEAYYQETGRAGRDGQTSVCVLYYAYADTNLIMRLIDEGDGTPEQKDHNRANLR
RVVQYCMNETDCRRSQVLHYFGEQFPREQCHKTCDNCLAPKNVEHRDITDLAKDATQLVK
AIQKDKGVTMLYAIDVFRGSKTQKIAGAGHDKLAHAGKGSSIDRGDCERLFQLLAAEQVL
GERYERNGLGFTNAYVTLGPRAQQLLSGKLTLQMGFTKGGKSGGGGGKKGKAPAKQKTID
ESYDHEQYGGEYVDELYDETTGVYDEVEEEWCVPVRSCLVFRRADRFSRRRDHLGRRVVR
SSTSGSLNGAAKAGQEDETQVLFRQLLDVRNQVQSCRSLDL