Protein Info for mRNA_2545 in Rhodosporidium toruloides IFO0880

Name: 10913
Annotation: K05767 IQGAP2_3 Ras GTPase-activating-like protein IQGAP2/3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1636 PF00307: CH" amino acids 336 to 446 (111 residues), 44.9 bits, see alignment 2.4e-15 PF00612: IQ" amino acids 699 to 716 (18 residues), 16 bits, see alignment (E = 1.7e-06) PF00616: RasGAP" amino acids 1011 to 1217 (207 residues), 125.2 bits, see alignment E=6.2e-40 PF03836: RasGAP_C" amino acids 1422 to 1560 (139 residues), 145.7 bits, see alignment E=2.1e-46

Best Hits

Predicted SEED Role

"D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4)" in subsystem Peptidoglycan Biosynthesis (EC 3.4.16.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.16.4

Use Curated BLAST to search for 3.4.16.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1636 amino acids)

>mRNA_2545 K05767 IQGAP2_3 Ras GTPase-activating-like protein IQGAP2/3 (Rhodosporidium toruloides IFO0880)
MSASLAATDLDRSPSLSSASSTSTTTTTSSAPLTPALSSTSTSEIYLSSPALPPSTPEKT
PFPRLSKTPTSASSPWKAGHRANGAGSKSFDAARAAWANLESEAVRSPSPERRGMGGTPF
ADSSNYRSSIAPGSPTRFSASPTRTRPALPTIPSDRPSYSPSSRAPASPSQAQTHSDRIL
SSAIFATRPTTPSLGPNSPLLGRETSLRRAGMGHKRAMTLPQLGLGRDGLPVPLSAGAGG
AEGGLGGEGGLVVEEDVPGLPGRARLSRPADSLTPSLGPSPSSVFHSSHGRPSTSSAAGP
KRSTTMSLLPSMAAKAIDRQRQGLVAYEYLCHLAEARDWLETHITTLPSSTPLWDPTDTI
NDFEQSLRNGYALAHLARSLGGERCQGPIYNDPVRHFRHTVNINIFFQLLDEVGLPEIFR
FETVDLYDAKNLPKVVYCLHALSHLMARRGLTDRMHDLVGQIEFTDAEVGAAQKGLSDAG
VRMPNFAGIGKALDKHESPPAAPPPETEGERRERLLSEAEGGVRGLQACARGVLVRRWVE
KERRRREVEERRRREEEAEARRRAEELEAQRRAEEAEARRRKEEEDARRAAEEEERRYQA
AVREAATTLVGFQAAARGAIQRRRFFAPIEQLAVHNETVTAFQAAARGTLARRELRQEIV
DLKDASPAVTAFQTACRGALARQALLDRIRHLRSAESFIVGVQSRIRGHLARQDYRSKAR
NLRKTEVVKSVGGLQSLARAALARRRVKTQRQELGFVEPDVVGIQAQTRGFLGRTAFLAW
HQHVHENEGIVVFLQSLIRGAVARNKYFAVHQHLQQNMSNVVRLQAAIRSRRQGSQYRQL
RVDKNVPVSTIKNFMRLLDDSEFDYRGELQLESLRKELVSAIRETQELEDDVKDLDTKIA
LLVKNKITHEVARAQRANKGTLAPLKRSSLLSAANDPFAGGTLDHHTQRKLDLYQQLFWH
LQTKPAYLAKLFANMSRMRVSEKTQKQIEATTFVMFGYAQGHREEFLLLKLFQRSIQEEF
ANLANMAAFVRGNFTFVRLLVHYGRGVQQRQYLAGALATEIKAVMGRQGLDLGTDPIAIY
QAELEREESRTGLPSQRPEDVDYAHALADRETNALFIQHLIALRKATTAFLRAIFTSTAR
MPFGIRYVAREIFRALRARFPNEPEHESLRIAGHVVYYRFLQPAIVAPETFGIVEGVVPP
IQRQNLGEVCKMLNQISVGRLFGSDQEYLMPMNDFITSSAAEFTQWIFELIHIEDAETYF
RADEYVDAAASRRPVIYISPNDIYATHSILVETLDVIAPEEDDPVRQILVELGGVPTASS
AELERARADEVALTLATRLLPHEDPDAESKHLFNQAKRRVLAILKVQHGNNLEAVLAQQV
TPEDEDAWIRIVEEEEEEERRLAHAQRRAVVPQMDDIRNMSFHQLKMATLSDIVELRRTG
MVAKNDKYQAILNAIAHDIRSKHHRRVQRQNELQTMHATLSSLKDKKRYLDDQIKSYHVY
IDQSMAGIQKKSKKRIVLPWSIQGVHQRQLEKQGKKYKFGSYKYTAQTLYERGVLLSIEQ
VSPKTFDKVSMTFSSDNVGVFEIKVEFTGKTLSAVELKLEDLLEAQWVGKQTVAIGEAVK
MNLVELLDLINRKFYQ