Protein Info for mRNA_2555 in Rhodosporidium toruloides IFO0880

Name: 10923
Annotation: K12736 PPWD1 peptidylprolyl isomerase domain and WD repeat-containing protein 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 622 PF00160: Pro_isomerase" amino acids 472 to 620 (149 residues), 168 bits, see alignment E=1e-53

Best Hits

KEGG orthology group: K12736, peptidylprolyl isomerase domain and WD repeat-containing protein 1 [EC: 5.2.1.8] (inferred from 59% identity to cci:CC1G_05429)

Predicted SEED Role

"Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)" in subsystem Queuosine-Archaeosine Biosynthesis (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (622 amino acids)

>mRNA_2555 K12736 PPWD1 peptidylprolyl isomerase domain and WD repeat-containing protein 1 (Rhodosporidium toruloides IFO0880)
MPLPAADAAVATKKRKVLKHEKLYLDHLPAADRYYKSLMHRDTLSQVAVTKTNFVITASI
DGILKFWKKQPVGVEFVKLYRTHLSPILAVGVSDDGKSCASLGADSGGRTAEDLEVKGSA
KVFDVENFDMINILKLPYVPRACCWVHNRNDGRILLAVSEYDSSAMRIYDGRGDGKPLHT
LSSMHRQSVHLMAYNSLHDTVISVDVGGMIEYWQPNEPFEKPDSVEWTSKAQTGLYEFKK
TKSTPVALTISPTHDSFAILSLPDLRLTIINFVTGRLHRAYDESLNAVQEMQQAGTAGVQ
LDSMEFGRRLAVEKELEKQALDSVLEGRAGSTATIGQPVWDEGGKFVIYPTMLGIKVVNT
VTNKVARILGKDETVRFNNLALYQGMPTKQGVKTIAMMTSENPLLADKDERDPTLFCTAW
KRPRFYMFTRSEPECVDKAGERDVYNEKPTRDEMTVAAPATSASGPLNRRAVIHTTKGDI
RVELFPDQVPKTVENFVGLSKKHYYDDVIFHRVIPKFMIQTGDPLGDGTGGESLWGHPFE
DEFHPSLKHDRPYMLSMANAGPKTNGSQFFITTVPCPWLDNKHSIFGRATGGFDVVHEIE
NARTDKGDKPFDEIKITSVSLE