Protein Info for mRNA_2569 in Rhodosporidium toruloides IFO0880

Name: 10937
Annotation: K07250 gabT 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00202: Aminotran_3
  • amino acids 18 to 435 (418 residues), 384.4 bits, E=2.7e-119

Best Hits

KEGG orthology group: K00823, 4-aminobutyrate aminotransferase [EC: 2.6.1.19] (inferred from 62% identity to lbc:LACBIDRAFT_190873)

Predicted SEED Role

"Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase (EC 2.6.1.19)" (EC 2.6.1.19)

MetaCyc Pathways

• 4-aminobutanoate degradation I (2/2 steps found)
• 4-aminobutanoate degradation III (2/2 steps found)
• GABA shunt (3/4 steps found)
• superpathway of 4-aminobutanoate degradation (2/3 steps found)
• 4-aminobutanoate degradation II (1/2 steps found)
• superpathway of L-arginine and L-ornithine degradation (7/13 steps found)
• superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation (5/11 steps found)
• 4-aminobutanoate degradation V (2/7 steps found)
• nicotine degradation I (pyridine pathway) (4/17 steps found)

KEGG Metabolic Maps

• Alanine and aspartate metabolism
• Butanoate metabolism
• Glutamate metabolism
• Propanoate metabolism
• beta-Alanine metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.19

Use Curated BLAST to search for 2.6.1.19

Protein Sequence (442 amino acids)

>mRNA_2569 K07250 gabT 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase (Rhodosporidium toruloides IFO0880)
MASLAQLGSKHVAKGVGRFTEMVMTEGKGTYIKTECGRTILDFTCGIGVTNLGHCHPKVT
KAAQEQVSTLVHGQVNLGYNKPYLQLIEKLLPVMPHKSLDSFFLWNSGAEAVEASIKLAR
HATGKQNIIVVQGSYHGRTFGTMALTKSKTIYGAGYAPLMPGVFTTPYPYWHQLGLPHTT
SNDDLVENALYRLELLLKQETAPRDTAAILIEPVLGEGGYIPAPKGYLEGLRRICDENGM
LLIIDEVQTGFGRTGKYFAIEHYPDVIPDIMVMAKGIANGFPLSGIVSRKELMDKQPAGS
QGGTYGGNAVSCAAGVAVQEAFKEEGILENVQARSEELFGMLKELQKDEKIGNCIAEVRG
LGLMVGIEFKSPTDRYTPAKSTVPAKMSSRVQNKCLEKDLLTLTTSVYETIRFIPPLNIS
KEDMAKACDIIKQAITDVVHEG