Protein Info for mRNA_2584 in Rhodosporidium toruloides IFO0880

Name: 10952
Annotation: K12350 SMPD1, ASM sphingomyelin phosphodiesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 696 transmembrane" amino acids 93 to 112 (20 residues), see Phobius details PF00149: Metallophos" amino acids 246 to 512 (267 residues), 41.1 bits, see alignment E=1.6e-14

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (696 amino acids)

>mRNA_2584 K12350 SMPD1, ASM sphingomyelin phosphodiesterase (Rhodosporidium toruloides IFO0880)
MGSPGAIAGRCETPGERSGLLADDTASGRRPDRHTAASTPLRSPSSSGFASRPRSIRSLA
SYGAVIDAHTPPVEDPEAVDVGRKSSWPGRLRTQLLVLSVVLLLSVCVYASFVDDFMGDV
EASVSCATCIGLLAPLQALARLGDDAFVDLFVGFCTKLGIEDADVCAGAVGTQAPILAHD
LRSIRLASPAAKNFCTTIFGLCPLPNTIPHTVNLTEPPIDAGAEMLDGHAPRRTRKIWRS
KGRSPFQVVHISDVHVDRSYTPGSSADCSKVICCRNYGPGSLGEAVKVPAGPFGHKKCDA
PPALVESMFRAIDKFAPNKSFTIFTGDVVESAVWAVDQAHVSDDLLRWNEDMQSPSYPVV
GNHDVAPVNAFPRSTSPQAHDSDWVFELAARDWGKWIGRDAAEQVRKMSGCYSRVHPGTN
LKIVSLNTNYWYKQNFWLYDSDEPVWDPNGILTWLAHELDLAEQAGQRAWIIGHMPFGKV
DAMRDQSNYANQIFQRYHNTIAAHFYGHSHVDEFEIAYPDYADRRAETANGVAFISGALT
PTSGNPVFRVYDIDPDTYEVVDFVPHYTNKSEPSFQVDPVWQPYYSARKSYGSYLDPPFP
DDAPLNATFWHRVTEVFERNETVFQLFNARLSRGGKIEDCSGPICKNNTICMLRSMRSES
NCAVIQPGLSFKDQKRDTDVSLGQRSQPTLLILAPL