Protein Info for mRNA_2643 in Rhodosporidium toruloides IFO0880

Name: 11011
Annotation: K01254 LTA4H leukotriene-A4 hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 636 PF17900: Peptidase_M1_N" amino acids 25 to 210 (186 residues), 73.9 bits, see alignment E=3.1e-24 PF01433: Peptidase_M1" amino acids 246 to 441 (196 residues), 128.2 bits, see alignment E=5.5e-41 PF09127: Leuk-A4-hydro_C" amino acids 516 to 626 (111 residues), 106.7 bits, see alignment E=1.2e-34

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (636 amino acids)

>mRNA_2643 K01254 LTA4H leukotriene-A4 hydrolase (Rhodosporidium toruloides IFO0880)
MAAIPTTRDNATQSNYQDIRTTALDLEWTVDWQHRIIRGHVKHSLKAEKDSVDKLILDTS
YLAIKRCYIPSSSHSDLSFSLPSKRHPNLGSALTITLPHALKKEEELEVVIEYSTTDGCT
ALGWLEKEQTDSKKYPFVYSQCQAIHCRSLCPIQDTPAIKTPYTATVHSPLPILLSALRV
SPPLEAPQPPIDGTLHTTKWHQPIAIPSYLLAIAGGEVAFRWLGERTGVWAEAGKVDACA
REFQEDAERFIKTAEELCGPYKWGRYDALVLPFSFPFGGMEHPNMTFLTPALIVGDRSQV
DVLAHEASHSWHGNDVGVAAWDSFWLNEGWTTYTERLIALRLHGPQTRDFEYIIGAKSMN
DDLKRYDRDGWRKAQRLHISYDFGEDPDEFYSSVAYDKGANFLYYLEKLVGGVEVFNPYQ
KAYIKEFGGKAVSTKDWEDHFWSYWNQYPEKARILKEKVDWDAWLNGEGTELPVKMEYDT
TLADRAYALASSWNSSRSLSPSDLASKFTNSDLEGMSSTQIVLYLETLGTYDKFEEKVVE
AVEKAYGFDGSHDPEIRLRWYLFALKSGLYAKQAAHWVRNQGRMKYCRPTYRAVFTVDPE
LAKETFLKYGKGFLHPIARRMVAQDLGLDEGEKKEK