Protein Info for mRNA_2673 in Rhodosporidium toruloides IFO0880

Name: 11041
Annotation: K10844 ERCC2, XPD DNA excision repair protein ERCC-2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 892 TIGR00604: DNA repair helicase (rad3)" amino acids 10 to 725 (716 residues), 894.5 bits, see alignment E=3.1e-273 PF06733: DEAD_2" amino acids 87 to 270 (184 residues), 192.4 bits, see alignment E=8.3e-61 PF06777: HBB" amino acids 287 to 430 (144 residues), 141.7 bits, see alignment E=3.4e-45 PF13307: Helicase_C_2" amino acids 541 to 715 (175 residues), 152.1 bits, see alignment E=2.6e-48

Best Hits

Predicted SEED Role

"Transcription initiation factor IIH p80 subunit" in subsystem RNA polymerase II initiation factors

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (892 amino acids)

>mRNA_2673 K10844 ERCC2, XPD DNA excision repair protein ERCC-2 (Rhodosporidium toruloides IFO0880)
MKFMLDDMEFVFPYDKMYPEQYNYVCDLKRSLDAHGHCVLEMPSGTGKTVSLLSLIVAYQ
YVRSLAQLQPNAFHERKMGRPERKLIYCSRTVPEIEKALAELKRLMQYRKEVYDIDDGDF
LGIGLSSRKNLCIHPSVRQEKKGKAVDARCRDMTSSVAKQRWEQDPTSVELCEFHENLGE
LDPDHLIPYGVHTIEDMKAYGQQHKICPYFAIRRMFVHANVVIYSFHYLLDPKVAEQVSK
HMSKDSIVVFDEAHNIDNVCIESLSIDLTRPMLDTAARSVETLTQKIEEIKEKDASKLED
EYRRLVEGLQAGENAVEDEDFMANPVLPQDLLQEAVPGNIRRAEHFTAFLARFVEYLKTR
MRVLHVVAETPLSFLQHLRDITFIERKPLKFCSERLSSLVRTLELTRIDEYSALQKVAAF
ATLVATYHEGFRLLLEPFETDNATVPNPVFHLVCLDASLAIAPVFERFSSVVITSGTLSP
LDMYPKMLRFDATVLESYVMTLTRDCFLPLVVTRGSDQVEISSRFEVRNDPAVVRNFGTL
LVEFCKAVPDGVVAFFPSYLYMESIVSAWNEMGILNEVLKYKLIFIETPDAVETSAALEN
YRRACDNGRGAVLLSVARGKVSEGIDFDHNYGRAVIMFGIPYQYTESRILKARLEFLRDT
YRIRENDFLTFDAMRHAAQCVGRVLRGKTDYGLMIFADKRFAKVDKRNKLPKWIGQYIKE
SDTNLATDVAIAHSKRFLRMMAQPFEQSTKSLWGIEEILDKQRGLDPDLGVDEDGAMLDA
EAEAAAQAEAEAAAAAEAEAEGLEPLDMNGLNGGEKVNGTNGLDGDAQMYDPEDDPYGEI
DDAALAEMDLPQDLDGFGLPQPPDEFQLPQSPQEFEMGDAQAGLPQPPPEFL