Protein Info for mRNA_2839 in Rhodosporidium toruloides IFO0880

Name: 11207
Annotation: K01427 URE urease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 854 transmembrane" amino acids 771 to 793 (23 residues), see Phobius details PF00547: Urease_gamma" amino acids 4 to 103 (100 residues), 124.6 bits, see alignment E=4.3e-40 TIGR00193: urease, gamma subunit" amino acids 5 to 104 (100 residues), 96 bits, see alignment E=2e-31 TIGR00192: urease, beta subunit" amino acids 144 to 242 (99 residues), 135.2 bits, see alignment E=1.3e-43 PF00699: Urease_beta" amino acids 145 to 240 (96 residues), 138.9 bits, see alignment E=1.2e-44 PF00449: Urease_alpha" amino acids 286 to 405 (120 residues), 180.7 bits, see alignment E=3.1e-57 TIGR01792: urease, alpha subunit" amino acids 287 to 854 (568 residues), 915.2 bits, see alignment E=2.5e-279 PF01979: Amidohydro_1" amino acids 411 to 740 (330 residues), 226.8 bits, see alignment E=1.3e-70

Best Hits

Swiss-Prot: 62% identical to UREA_ASPFU: Urease (ure1) from Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)

KEGG orthology group: K01427, urease [EC: 3.5.1.5] (inferred from 62% identity to afv:AFLA_029380)

Predicted SEED Role

"Urease alpha subunit (EC 3.5.1.5)" in subsystem Urea decomposition (EC 3.5.1.5)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (854 amino acids)

>mRNA_2839 K01427 URE urease (Rhodosporidium toruloides IFO0880)
MGFDLLPREIDKLQLISLAGQLAQKRLARGCRLNVTEATALIAHVLQELIRDGDHSVAEL
MSIGKKILGRVHVQPAVPSLLHEIQVEGAFPDGVFLVTVHDPISSASVNDDLSLALYGSF
LPLPKEGVFPKGSDEPAGPADEEIPGALVLRKEPIRINEGRERVRLKVTNTGDRPIQVGS
HYHFTEVNRALSFDRRKAFFKRLDIAAGTAVRFEPGDTKTVTLVQIGGEQVVTGGNLLLN
SSVARHLADPSLADSSMQRIISSGFSHVDDPSAVLTSDTSLIVPFEVSRETYASMFGPTT
GDRVRLGDTSLWVEVERDETHYGDECKFGGGKVIREGMGQATGLPDAETLDLIITNALII
NWDGIYKADIGVKTGHIVGIGKGGNPDVMNNITPGMVVGVNTDVIAGEKLIVTAGAIDAH
VHYICPQLCNEALASGITTLLGGGTGPSAGSNATTCTPSRTYMHTMMAATDGIPLNFAFT
GKANDSGEAGLEDQVRNGAVGLKLHEDWGSTPAAIDSALSLAEKYDVQVNIHSDTLNESG
FVQDTIDAFKGRTIHAYHIEGAGGGHAPDCCRMISLSNVIPSSTNPTRPFAPNTLDEHLD
MLMVCHHLDRSIPEDIAFAESRIRAETIAAEDVLHDSGAISIISSDSQAMGRIGEVVSRT
WRTASKMKDVVGTLKEETRDGADNERVKRYIAKYTINPAIVHGMSHVIGDVSVGKLADLV
LWQPAYFGVRPNMVVKGGVIAWANMGDANASIPTVQPVIGRPMWGSQPSAAALTSLLFVS
SLSLSSGTIASYGLKKRPVAVKGCRKVRKEDMKNNSALPKIEVDPESYKVTADGVHCTVP
PATKVPLAQSYMLF