Protein Info for mRNA_2848 in Rhodosporidium toruloides IFO0880

Name: 11216
Annotation: HMMPfam-GMC oxidoreductase-PF00732,HMMPfam-GMC oxidoreductase-PF05199,PIRSF--PIRSF000137,ProSitePatterns-GMC oxidoreductases signature 2.-PS00624,SUPERFAMILY--SSF51905,SUPERFAMILY--SSF54373

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 635 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details PF00732: GMC_oxred_N" amino acids 54 to 366 (313 residues), 206.1 bits, see alignment E=1.2e-64 PF05199: GMC_oxred_C" amino acids 490 to 627 (138 residues), 91 bits, see alignment E=1.6e-29

Best Hits

Predicted SEED Role

"Choline dehydrogenase (EC 1.1.99.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (EC 1.1.99.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.99.1

Use Curated BLAST to search for 1.1.99.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (635 amino acids)

>mRNA_2848 HMMPfam-GMC oxidoreductase-PF00732,HMMPfam-GMC oxidoreductase-PF05199,PIRSF--PIRSF000137,ProSitePatterns-GMC oxidoreductases signature 2.-PS00624,SUPERFAMILY--SSF51905,SUPERFAMILY--SSF54373 (Rhodosporidium toruloides IFO0880)
MAPRQRQSRTTTSTTALALAAFVALVATPAANGLTLDLVANSTAVASTLNSTQFDYVVVG
GGNAGLAVASRLSSSYNVLVLEAGTDQSGNAGVTVPGLAGSPLGSGIDWGFSTVPQSNAD
GRSVYWPRGKMLGGSSGLNFLVSTRPNKAELDQWSSLSGSSSWSWSSLFPYFKKTERFYS
PCATKPEGVTPTYNSYVHGYSGPMAISYPPYLGKQNNGFYQAVQQMGVPVAQDLHTGSNH
GVNLSPSTEHDTGTDRTRAYSVDYLKLATSRLTVITSAQATKINWTGNKDASGNVVAQGV
SFVPVGGGSSSSVNVNKEVILSAGTVQTPQLLELSGVGDSSVLSGAGVSSVVNLPAVGTN
LQDHACIVDVFKLKPGVDSLDELSSNQTALGAALADFSNGQGILTQALYPLAYLQKQDFL
STDDINNQLPNLGSRANNPQLTDAQYQAATALYNANVPIMELLAINTYFGNSSAQPNTNY
ISLAACLQNPLSRGDIHISTSDPLAKPTINPRYLQSPLDGFLLARAGQFLRNTAAKGPLA
QYIDSEAEPGTGVQSDAEWAEWVKSVVRTEYHPIGTASLQSQSAGGVVAPNLKVYGTSNV
RVVDLSVAPLHVSSHTQTVAYAIAEMASSMILAGK