Protein Info for mRNA_2849 in Rhodosporidium toruloides IFO0880

Name: 11217
Annotation: K01611 speD, AMD1 S-adenosylmethionine decarboxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01536: SAM_decarbox
  • amino acids 21 to 492 (472 residues), 393.3 bits, E=5e-122

Predicted SEED Role

"S-adenosylmethionine decarboxylase proenzyme (EC 4.1.1.50), eukaryotic" in subsystem Polyamine Metabolism (EC 4.1.1.50)

MetaCyc Pathways

• superpathway of arginine and polyamine biosynthesis (13/17 steps found)
• spermidine biosynthesis I (2/2 steps found)
• spermine biosynthesis (1/2 steps found)
• superpathway of polyamine biosynthesis I (5/8 steps found)
• L-methionine salvage cycle III (7/11 steps found)
• superpathway of polyamine biosynthesis II (4/8 steps found)
• spermidine biosynthesis III (1/4 steps found)
• L-methionine salvage cycle I (bacteria and plants) (6/12 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Methionine metabolism
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.1.50

Protein Sequence (497 amino acids)

>mRNA_2849 K01611 speD, AMD1 S-adenosylmethionine decarboxylase (Rhodosporidium toruloides IFO0880)
MAAVHQDATVTVVDDSSPGPFEGPEKLLEIWFAPSEEDVLRRNLPLKGGRAAAASSSTSA
AAAHRDRWVGLRQVEKSVWDGMLDEVCCKVLSVIEGEEVDAYLLSESSMFVWPHKIILKT
CGTTTLLLGIPTLLRIASETCGFQGVWRCFYSRKTFMFPERQKGPHKDWSAEMSFLDKLF
ENSSAYTVGRMNGDHWLLYVTPPRDDVLLPHAMESSAALAPANPHTDLSTLSASLSTTPS
AFPTPRRQHSSTAIIPSTSSGPRAPSRPDQTLEILMTGLSPRACQKFYHPSSTPSAPIPY
TSPLYPTDPLVIDGDAHHLGSKLSDDLGLTALLPGATIDSFLFAPCGFSQNAVRGDRYAT
VHVTPEEAYSYASFECNFDFGGLASSVDAKDQDEGVAGLDTIEGVRRTTESLQELVERVL
EIFEPAKMTITLFVSDEDDDAESINEGGSDKRARTHEGMKQLLSPELAEKYERVDRILYV
LEGYSLVYQVFQTRQQR