Protein Info for mRNA_2898 in Rhodosporidium toruloides IFO0880

Name: 11266
Annotation: KOG0054 Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1579 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 30 to 50 (21 residues), see Phobius details amino acids 102 to 123 (22 residues), see Phobius details amino acids 142 to 160 (19 residues), see Phobius details amino acids 172 to 193 (22 residues), see Phobius details amino acids 201 to 222 (22 residues), see Phobius details amino acids 340 to 361 (22 residues), see Phobius details amino acids 380 to 398 (19 residues), see Phobius details amino acids 410 to 426 (17 residues), see Phobius details amino acids 487 to 512 (26 residues), see Phobius details amino acids 582 to 605 (24 residues), see Phobius details amino acids 617 to 640 (24 residues), see Phobius details amino acids 992 to 1013 (22 residues), see Phobius details amino acids 1033 to 1057 (25 residues), see Phobius details amino acids 1116 to 1148 (33 residues), see Phobius details amino acids 1222 to 1247 (26 residues), see Phobius details PF00664: ABC_membrane" amino acids 455 to 629 (175 residues), 73.5 bits, see alignment E=3.5e-24 amino acids 996 to 1229 (234 residues), 108.8 bits, see alignment E=6.3e-35 PF00005: ABC_tran" amino acids 720 to 853 (134 residues), 58.4 bits, see alignment E=1.8e-19 amino acids 1323 to 1482 (160 residues), 104 bits, see alignment E=1.5e-33

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1579 amino acids)

>mRNA_2898 KOG0054 Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily (Rhodosporidium toruloides IFO0880)
MMLVLGGCAPALSLTTPARLAVHPALALAPHLLLALSVISSIAWVAWVHIRAARRPSTAR
GTDDNGTGDSPEERQPLLDGEDDSVRSGVKLRGEDSEGPTGWELLLGIAKVLVAVALVGV
TVGKLLGVEDGASTRWTRVFEGGMIAVPAYVVLLSAAIIAEHRLARLVHIQQAALSSGLV
LLSTAVFVWPFLFFDHPALTAAWRLGFVQAALAMALFLIMLATPTRYQPRLTGASPNPAQ
TASPLSRLFFSFLESRMVCYYAATSPRLTRFLRLHSVKDFASYVPPLSDVLHSDYVLRRF
RWTGDAVNKSRDDDEDGEQEKPAPRTGEILQFAMENKKDLLVIVAFATSWIGWIFVTPLS
MNLLLRYVQQSESPPFGLSPYLFVVLIFVAPIASSVSYQSALYRLAQLGLRLRALLGHAI
YAKLLRIKAGGGSEKHAEKGKSSKKTSGAGGSEAVGRVNNLVGTDIDGITSSLPSALQLL
GVLPKLVVSLVFLYFLLGWSAFVALGSIVLFAPISNVVSRRYGAVQEEIMQATDKRITLV
QELLNSIRTLKMFAWEEPSMKRISDARDVELGRITKRAKVYGGMMFLSTGVPAVVTLSTF
GAYIFLQHQSLTASTAFTAMSLFGLLREAVISATYLLSAFMRARVSLGRISRFVRDTEEL
DASARTFADSPFTDRSTATEGDAADDSAIVIEADSTFRFSRYDDAAFTLKLSGDGGSALV
FPRGKTTIIAGDVGGGKSALLLALLGELHVVKGGVQLSLPRRDGAPKVSFAAQSPWLQDT
SVRQNILFGEEYDDERYRETIFACALEDDLEALPEGDETRVGERGLSMSGGQKQRIALAR
AVYARSDIVLLDDVLSALDSNMVQHVVEHCLDGPLLEGRTVVLVTHFTSLCVRKLRRCAL
VVDLHDGKVTKAAAPSTQLEAKSNGMTRSSSSTSLRSERSDPSKGSKDGFHAAEVKHGHG
VVEDRIDSSGEGTDISWTVYRKYAAAMGGLKFWIPYAVVNIVAHVFMLAQGWFVGRWVGA
PDRDSHAARYFSLYAGIQIVASVSLTAMYLLLIWGGIRASRLMHRRLTDRIFAAPFRWWD
RTPVSHAINRFSKDTEVLDTEQVENLSPVLDYGCQVLFVAVVICVALPIFLLPAAIISAV
FFCIGRLYVRNALAARKEVAAARAPLFSTLGDSTSGVTTIRAFGRQEHFARRYKEQTDTY
NQVQLYAEGLDRWLEERSDMVGATVSFIVGLLCLSSGLSSGVTGFLISTGLEFTSRILYV
VRAVNKNELSLNSVQRIIQYSTEVETEEPASDKKEPPAHWPDSGAIEFKSFSAKYSEKGD
DVLHELSLSIKSGEKIGIVGPSGCGKSTLSLALLRFILTSKGSIEVDGRRLSDTNLQAIR
SRFTLVPQDPTLFSGTLRSNLDPNGEHDDATLWNAIKRSGLTRAGSTDAPDGDADTSTTG
LSLDTPVASSGSNFSQGQRQLIGLARALVRNSKVIVMDEATASLDNESDELVQRVIREEF
KGCTNLTVAHRLETIIDFDRVLVLRAGKVVEFDAPSALLDKEDGVFREMVEATGDFDELK
RKAQEGKVKGWSESKGARS