Protein Info for mRNA_3095 in Rhodosporidium toruloides IFO0880
Name: 11463
Annotation: K01739 metB cystathionine gamma-synthase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"Cystathionine gamma-synthase (EC 2.5.1.48)" in subsystem Methionine Biosynthesis (EC 2.5.1.48)
MetaCyc Pathways
- superpathway of sulfur amino acid biosynthesis (Saccharomyces cerevisiae) (9/10 steps found)
- L-methionine biosynthesis II (5/6 steps found)
- superpathway of L-cysteine biosynthesis (fungi) (5/6 steps found)
- superpathway of S-adenosyl-L-methionine biosynthesis (7/9 steps found)
- superpathway of L-methionine biosynthesis (transsulfuration) (7/9 steps found)
- superpathway of L-homoserine and L-methionine biosynthesis (6/8 steps found)
- homocysteine and cysteine interconversion (3/4 steps found)
- L-methionine biosynthesis I (3/5 steps found)
- superpathway of L-lysine, L-threonine and L-methionine biosynthesis II (10/15 steps found)
- L-cysteine biosynthesis VI (from L-methionine) (3/6 steps found)
- superpathway of L-lysine, L-threonine and L-methionine biosynthesis I (10/18 steps found)
- aspartate superpathway (15/25 steps found)
KEGG Metabolic Maps
- Biosynthesis of plant hormones
- Cysteine metabolism
- Methionine metabolism
- Selenoamino acid metabolism
- Sulfur metabolism
Isozymes
Compare fitness of predicted isozymes for: 2.5.1.48
Use Curated BLAST to search for 2.5.1.48
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (774 amino acids)
>mRNA_3095 K01739 metB cystathionine gamma-synthase (Rhodosporidium toruloides IFO0880) MPTAFRVQPPPPSHVGDLVPADTPHAVSVALPTWQDNVDYEEGEQRVKDAMTSGYPRFFI HHRIQALADLACAKFGQPDELCILLPTESTARGCSSFLSSRSPHVQSRIVSWPIHAVSSS SPTDSTPSASAATRTITVWACFFPSSDFPAAKQYWQHTGEGISSRVAERCLILLGEIEAD SNGATGGAGASPTQATPSQAGPGQEGATRFFVNGGGNGAVNGGRYASSKSRYQVAKGSAT TPPVAAGIEVARPTVSSKLRYSTSKVRATNGGDSGEATPSSSEANSLANSIEQLPMPSAS SSRRPSQDASSSSPLPTPATPLLAMTNGTSLVEQDEDVLARYVEERYGRNLDLSLAPLAK LAMRRRIAGVLREGPGEAIPVQDMTGAKREESTRGVTGLTEDDVWLYPCGMNAIFHAHQV AMEAWKREGREVGKSVCFGFPYTDTLKILEKWGPGCHFFGRGLTSDLPSLRQTLQQSSPP ILALFCEFPSNPLLRSPPLHELRKLADEFGFLIVVDETIAGFVNVEVLPLADIVVSSLTK VFSGDSNVMGGSLVLNPKAPHYAALKTAQEATYEDAYFDEDAIYMERNSRDFQARVAQEN STAEMLCDFMRSRRVPGPAATGVIDELKREELANGAETSEFVVTEVYYPKYMTPEHYLAS LRPPNPSLGPKSSGFGALFSLTFSSILASRTFFDALPCYKGPSLGTNFTLACPYTILAHY TELEWAKEWGVEKGLVRISTGLEEPEVLRQWFEEALEKAERAVREAKERGETVE