Protein Info for mRNA_3118 in Rhodosporidium toruloides IFO0880

Name: 11486
Annotation: K01881 PARS, proS prolyl-tRNA synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 711 TIGR00408: proline--tRNA ligase" amino acids 214 to 711 (498 residues), 602.3 bits, see alignment E=3.5e-185 PF00587: tRNA-synt_2b" amino acids 310 to 478 (169 residues), 60.4 bits, see alignment E=3.7e-20 PF03129: HGTP_anticodon" amino acids 498 to 596 (99 residues), 70.3 bits, see alignment E=1.8e-23 PF09180: ProRS-C_1" amino acids 625 to 711 (87 residues), 87.6 bits, see alignment E=7.5e-29

Best Hits

Predicted SEED Role

"Prolyl-tRNA synthetase (EC 6.1.1.15), archaeal/eukaryal type" (EC 6.1.1.15)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.1.1.15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (711 amino acids)

>mRNA_3118 K01881 PARS, proS prolyl-tRNA synthetase (Rhodosporidium toruloides IFO0880)
MDVQQLTQRIEQLGIAASPAAAGSAGSQLLSYFFTPKSGSKHPDNAEQDLKLVVAAIEEE
KNLGPAKALAASVGLKDMRAVSGADLEKLLGRTRDQASPLSLPPSLAPSTLLITSTSLSS
ASTVSLPSPSDPSQSLSLSNEEWHKALLQLKQEGVALKEAEFFLKGVEPPKPAAQKAAGA
PASTASTSAAAGRVAQADLEGQAGVQLGLTVKKEQSVFGDWYQQVLIKGEMLDYYDISGC
YILKPWSYGIWQEIQTWFDRHIKALGVSNAYFPMFVSSTVLEREKDHIEGFAPEVAWVTR
AGKSELEVPIAIRPTSETVMYPYYGKWIRSHRDLPLKLNQWNSVVRWEFKNPQPFLRTRE
FLWQEGHTAFQTKAEADEEVLQILDLYRRVYEELLAVPVIPGVKSEKEKFAGGLYTTTVE
GFIPTTGRGIQGGTSHCLGQNFSKMFNITVEDPANPGGDKLHVWQNSWGLSTRSLGVMVM
VHGDDKGLVLPPRVAQLQVVIIPVGITAKTTEDMRKKIEDEADRIAKELVKQGLKAKADL
RDGYTPGFKYNDWELKGVPIRLEIGPKDLEKQSVMSVRRDNGVKGALPIADLSSSVPALL
EQIHHDMLNRARETFDKSIVKVEEWEKLVPALNGNNIVVIPWCEAEKCEDEIKDRSAKES
VSGAEDERAPSAGAKSLCIPHDQARFGSVEGKSCPNCGEKAKRWTLFGRSY