Protein Info for mRNA_3173 in Rhodosporidium toruloides IFO0880

Name: 11541
Annotation: K09497 CCT5 T-complex protein 1 subunit epsilon

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 548 TIGR02343: T-complex protein 1, epsilon subunit" amino acids 11 to 542 (532 residues), 911.8 bits, see alignment E=6.9e-279 PF00118: Cpn60_TCP1" amino acids 47 to 542 (496 residues), 510.3 bits, see alignment E=2.7e-157

Best Hits

Swiss-Prot: 73% identical to TCPE_SCHPO: T-complex protein 1 subunit epsilon (cct5) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: K09497, T-complex protein 1 subunit epsilon (inferred from 77% identity to lbc:LACBIDRAFT_317939)

Predicted SEED Role

"Heat shock protein 60 family chaperone GroEL / Thermosome subunit" in subsystem GroEL GroES or Staphylococcal pathogenicity islands SaPI or Thermosome, archaeal

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (548 amino acids)

>mRNA_3173 K09497 CCT5 T-complex protein 1 subunit epsilon (Rhodosporidium toruloides IFO0880)
MQGLPQNAQYAVDEYGRPFVIIRDQGKRTRLHGLEALKSHIRAARTVSNIVKTSLGPRGL
DKIMISPDGDITVTNDGATIMGQMQVEHEIAKLLVELSKSQDDEIGDGTTGVVVLAGALL
ESASALLDRGIHPIKIADGFDRACAVAVAELDRIGDVIPYSREETGELLKVAQTSMGSKI
VSKAHDLFAKIAVDAVLSVADLDRKDVPFDLIKVSGKVGGSLEDTTLIRGVLLDKDMSHP
QMPRSITDAKLAILTCPFEPPRPKTKHKLDITSVEEFKKLQEYEMEKFQTMIRQVKDTGA
NLVICQWGFDDEANHLLMQNDLPAVRWVGGPEIELIAIATNGRIVPRFEDLSAAKLGHAG
VVREVSFGTTRDKMLVIEDCANSKAVTVFVRGSNKMIVDEAKRALHDALCVVRNLVRDNR
VVYGGGAAEIACSIAIANEADKVASIEQYAMRAFATALDAVPLALAENSGLAPIETLAEV
KSRQVTEGNSRLGVDCLGKGDSNVADMKDQLVVDPLLSKRAQLLLATQLARLVLRIDDCI
IQGQADEY