Protein Info for mRNA_3175 in Rhodosporidium toruloides IFO0880

Name: 11543
Annotation: K01191 E3.2.1.24 alpha-mannosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1143 PF01074: Glyco_hydro_38N" amino acids 292 to 548 (257 residues), 248.2 bits, see alignment E=2.4e-77 PF09261: Alpha-mann_mid" amino acids 566 to 669 (104 residues), 87.6 bits, see alignment E=1e-28 PF07748: Glyco_hydro_38C" amino acids 772 to 984 (213 residues), 170.3 bits, see alignment E=1.3e-53 PF17677: Glyco_hydro38C2" amino acids 1044 to 1138 (95 residues), 24.2 bits, see alignment E=6e-09

Best Hits

Predicted SEED Role

"Alpha-mannosidase (EC 3.2.1.24)" in subsystem Fructooligosaccharides(FOS) and Raffinose Utilization or Mannose Metabolism (EC 3.2.1.24)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.24

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1143 amino acids)

>mRNA_3175 K01191 E3.2.1.24 alpha-mannosidase (Rhodosporidium toruloides IFO0880)
MAMHGPPPPPSYPMINNDGPRAQHFRGLTLGRLDQFESSNYPNITSVLFQHRTDDPQHVQ
LEVWHSPGREKTPFKEAIRKKFVKAEKGMMLGPSWTNHWFRLTLTPPSSWLTSSAPPERI
QLEFDPSCEAMIFDTEGCPLQGITGGFGIDRRVEWLVPREKWKTGLKIYIEVSNNAMFGN
GSTETNAPPDMNRYYRLNSADLVVPRMEAWRLLWDFRVIKDLARSLPDRSPLGAKCLEVG
NAIMNTFNPSDLSTLSTCRALAAPLFGGEEWTREGGEAKVYEKGRESVTSWAIGNCHIDT
AWLWPFSVTRQKTARSWSTQLDLIARYPEHRFVVSQAQQFKWLEQDYPLLFQKVRKGVQE
GKFIPIGGMWVESDQLLPSGESLARQFLYGQRYFHSRFGQYCKTWWLPDSFGYNSASPQI
ARLAGLEFFFTQKLSWSQFNEFPNTSFRWQGQDKTQMVVHMCPQNTYTAQASVDDVLNTW
RNHKSLQSHPTGLLTFGNGDGGGGPLAPMLENLRRCRAVANNAEMGGGEIPKVHMGEEVD
QFYEDLVRRTKGAEKLPVWVGELYLELHRGTATSHGSIKRHNRKTEVLLHDLEFAATLAT
VFGAQTKSGKAYAYPKDEIDALWEDMLLCQFHDVLPGSAIGMVYEDAEKIYASVTEKGST
LLDAALSALLPGSVSLTSESSSSFGLDSSLVAIDTLALGTRRELVKVPLAAARALDDAAV
QRSADGEAYVLFESSKEGEMVIEKPIGTGEVMRRANELTSRARSVGDDFVLSTPKLQVTV
TKDGRISSIFDKELERELILEDKTTGFVIFQDHPLNWDAWDVDAFHLETKKDVNASSVKV
IEDGPLRSSLLATYHYGKSVIKATISLDAAAPSTKADALSLVRFDVQVDWHQCHEFLKWE
LPLAITPTGDVATFENQFGLCQRPTHRNTTWQRAQFEVCGHRYADLSEFGYGVALVNDCK
YGHACENSTLRLSLLRAATIPDAEQDQGQHRFSFAVYPHRGAFAESDVPDVARAFNYPLH
IRRLPGKAVKSPKEGPFFLTGAGNVILDTIKRGEDDHFGAKAKGESETVVLRMYEAYGGA
GKVKLEAKLPEGRRVVKAEIVDLLERPVDSLKILTAASSPSSHSIDMPRLRAFQILTVRL
TLG