Protein Info for mRNA_3193 in Rhodosporidium toruloides IFO0880

Name: 11561
Annotation: K13116 DDX41, ABS ATP-dependent RNA helicase DDX41

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 637 PF00270: DEAD" amino acids 224 to 403 (180 residues), 147.1 bits, see alignment E=7.1e-47 PF00271: Helicase_C" amino acids 439 to 545 (107 residues), 91.2 bits, see alignment E=8.6e-30 PF00098: zf-CCHC" amino acids 598 to 614 (17 residues), 21 bits, see alignment (E = 4.1e-08)

Best Hits

Swiss-Prot: 57% identical to DDX41_HUMAN: Probable ATP-dependent RNA helicase DDX41 (DDX41) from Homo sapiens

KEGG orthology group: K13116, ATP-dependent RNA helicase DDX41 [EC: 3.6.4.13] (inferred from 66% identity to scm:SCHCODRAFT_65679)

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (637 amino acids)

>mRNA_3193 K13116 DDX41, ABS ATP-dependent RNA helicase DDX41 (Rhodosporidium toruloides IFO0880)
MADTVQDQQEQPAQQPTYTRRRRTPTPPPPDPYAILDEDESAPLYVPLKQRRAQLVSKLA
AKGTGGAAAAAEKRKREELEEEEKERERDEEEARRKKREAQTLLMEAQEVKRQKAIEESA
KTEQQKREEEEAKILAAQEATRKKLAGAEEVAKGIVYTERMKATWRPPHYIRGKSEEELE
AIRDKFHILVSGDDIPPPIPNFRDMKLPKPLLEYLKKKKISAPTPIQLQGLPVAFSGRDM
IGIAFTGSGKTLAFSLPLLMLALEEEKRLPFMQGEGPVGIIMCPSRELARQTFEGLNEMA
RCLEQGGYPQVRSLLCIGGISMAEQGQTLANGFHMVVATPGRLQDMLEKRKFTLNQCKYL
CMDEADRMIDMGFEEDVRNILSFFKHQRQTLLFSATMPKRIQDFAQSALVQPILVNVGRA
GAASLNIIQEVEYVKQEAKMVYLLECLQKTAPPVIIFSDNKNEVDDIQEYLLLKGVEAVA
IHGSKTQEEREYAIKSFKSGKKDVMVASGVASKGLDFSEIQHVINFTMPKEIEDYTHQIG
RTGRGDKTGIATTFINMQTPEQTLLDLKYLLMEAKQKVPPFLLSIEDPNVGADGKPIGCT
NCGGLGHTIRNCPKLEENQRRTMAGIGRGGDSGGGGW