Protein Info for mRNA_3349 in Rhodosporidium toruloides IFO0880

Name: 11717
Annotation: K13179 DDX18, HAS1 ATP-dependent RNA helicase DDX18/HAS1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 540 PF00270: DEAD" amino acids 37 to 208 (172 residues), 158.8 bits, see alignment E=1.9e-50 PF00271: Helicase_C" amino acids 252 to 355 (104 residues), 82.8 bits, see alignment E=3.4e-27 PF13959: DUF4217" amino acids 395 to 455 (61 residues), 66.9 bits, see alignment E=2.3e-22

Best Hits

Swiss-Prot: 78% identical to HAS1_USTMA: ATP-dependent RNA helicase HAS1 (HAS1) from Ustilago maydis (strain 521 / FGSC 9021)

KEGG orthology group: K13179, ATP-dependent RNA helicase DDX18/HAS1 [EC: 3.6.4.13] (inferred from 81% identity to uma:UM04233.1)

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (540 amino acids)

>mRNA_3349 K13179 DDX18, HAS1 ATP-dependent RNA helicase DDX18/HAS1 (Rhodosporidium toruloides IFO0880)
MTGAKAAPEPKSRAFSSLDLSEGTRKAIEGMGFKEMTEVQARTIPPLLAGKDVLGAAKTG
SGKTLAFLIPAIEMLHRLKFKPRNGTGAIVVTPTRELALQIFGVAKELCEHHNQTFAIVM
GGANRKAEAEKLAKGVNLLIATPGRLLDHLQNTKGFVFSNLRALIIDEADRILEIGFEDE
MRQIVALLPKENRQSMLFSATQTTKVTDLARVSLRPGPLYINVDTKSETSTANNLEQGYV
VCDSDKRFLLLFTFLRKNLKKKVIVFFSSCKSVQYHGELLNYIDVPVLDLHGKQKQQKRT
NTFFEFCNAPTGILLCTDVAARGLDIPKVDWIIQFDPPDDPRDYIHRVGRTARAGKQGKS
LLFLLPSELGFLRFLKVAKVPLNEYSFPNDKIANVQGQLEKLIAKNYYLHQSARDGFRAY
IQSYASYSLKTIFDVTQLDLAKVAKAFGFSTPPAVNINVGRSAKGKKRKDHPKAGESSEE
ESESEEEVENERERRAKMARRGGGNQAKRRELEGKKAEKDFYREQGREKLKNAGGTQWSR