Protein Info for mRNA_3450 in Rhodosporidium toruloides IFO0880

Name: 11818
Annotation: K20131 RABGEF1 Rab5 GDP/GTP exchange factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 866 PF18151: DUF5601" amino acids 317 to 393 (77 residues), 42.4 bits, see alignment E=1.1e-14 PF02204: VPS9" amino acids 496 to 594 (99 residues), 110.5 bits, see alignment E=6.7e-36 PF02845: CUE" amino acids 826 to 866 (41 residues), 42.4 bits, see alignment 6.7e-15

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (866 amino acids)

>mRNA_3450 K20131 RABGEF1 Rab5 GDP/GTP exchange factor (Rhodosporidium toruloides IFO0880)
MDADKVSEPPAYPDLAPLAASLDTPPQPTPEPSDSSSNPSDIWATLPSTSKPFHEPAQTM
SAPGYHASYAVPAPAPPPPPVDWHDLDPFAPAHGTLGSTVRRESRLEVIENSESEEGSPV
EDRRMRDQQELGKGQQAQGQGSAAFSFGNMLRSFSGTPTKEREKTAPSQAHPELPAGHPS
ASTSSAASSSQASTSHPAPQTPTGPSPLAKPLASIASVFRSSNRPSPSSSTTSTPQPGSS
PQREKGMFIAAIAGSGAAKGKEKEKHVEEEKTDQADEKAALRQAGGDGRGREREEPVFDF
NKFLEQMRSRSADPIAKYLRSFLKEFSRRPPVSTNDQVRVINDFLDFIAGKMRHTDPWKS
MLDVDWRDDPERAEQEFDLAMEAMEKLVMNRLWHLTYTPALDLSAFPGHMSPSGDVERDD
VLRQRIRLFSWIEPKHLDLPIPSPSDPPPPEVFPKEGQSDTSEPSATHNKPVGDGKDAAK
KQQGGRKQIQGFLDFAQRELRKMNQYKAPRDKLICVLNCCKVIFGLIRHIASGEEGADTF
IPFLIYVVIKANPDHLVSNLQYIQRFRNPEKLSGEGGYYLSSLNAAISFIESLDASSLSN
ITQQEFESKVAAAVKQLASEEPPPPPPPHDPPTTSRSSTPSTRPPARDATATSSDLIQPS
EAASASLLAPTGEGGVAPATPQNLSFPETMKQSLIRGTDSVERAMSKPLGALARVFAQLE
ETANELTGQTPPPTPGVVRAPPAPLPPTPSVEHPQAGHPGSQRPHPSKRRSYHASLSRPP
LPPLPPSSGSLQTAAPPPDLSMYAAPDVSDDVVLREIDRQHEEARMAQLETLQSIFPDAE
REVLEMVLLSNSGDMGKTIDSLLEMT