Protein Info for mRNA_3458 in Rhodosporidium toruloides IFO0880

Name: 11826
Annotation: K03857 PIGA, GPI3 phosphatidylinositol glycan, class A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 488 transmembrane" amino acids 413 to 438 (26 residues), see Phobius details PF13439: Glyco_transf_4" amino acids 35 to 203 (169 residues), 97.5 bits, see alignment E=3.3e-31 PF13579: Glyco_trans_4_4" amino acids 36 to 200 (165 residues), 63.7 bits, see alignment E=1e-20 PF13477: Glyco_trans_4_2" amino acids 43 to 176 (134 residues), 35.2 bits, see alignment E=4.4e-12 PF08288: PIGA" amino acids 61 to 152 (92 residues), 120.2 bits, see alignment E=1.7e-38 PF00534: Glycos_transf_1" amino acids 218 to 359 (142 residues), 92.3 bits, see alignment E=9.6e-30 PF13692: Glyco_trans_1_4" amino acids 221 to 360 (140 residues), 89.7 bits, see alignment E=8.1e-29

Best Hits

Swiss-Prot: 48% identical to PIGA_MOUSE: N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein (Piga) from Mus musculus

KEGG orthology group: K03857, phosphatidylinositol glycan, class A [EC: 2.4.1.198] (inferred from 52% identity to lbc:LACBIDRAFT_191321)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.198

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (488 amino acids)

>mRNA_3458 K03857 PIGA, GPI3 phosphatidylinositol glycan, class A (Rhodosporidium toruloides IFO0880)
MDHGDPSSKRREFLSSSSTRSLNIALVSDYFFPKVGGVESSIYSLAQSLVKRGHRVVVIT
HAYPPRSGVRWLPNGVKVYYIPVQPLPPTHVHATLPNFFTAFPWIRSIFTRESIDVVHAH
AALSALGMETIMHARTMGVKAVFTDHSLFGLGNMAEIWGNKMLKGCLSDVEAVTCVSHTS
KENTVLRGALNPSLVHVIPNAVVVSQFRPAEPVPPVPDTLTIVCISRLVYRKGIDLLIAA
LPKVCALHSDVRFLIGGDGPKIVELDQMRDKYQTLLRDRVELLGPVKHEDVRELLSRAQI
FLNPSLTEAFGIGILEAACAGLFVVSTRVGGVPEVLPPGLVEFAEPDVDDLVRAISRAIT
HVRSGSHDPPLAHDQLRQVYSWTDVAERTERVYHHAMSVPRVPVVERLRRYYGTGAVFGK
IMCIIIIVDYVLLAIMDWFSPRDKIDRAPKFDLERWKRICREELEKEKKADARQAQEAEE
AKDGGGII