Protein Info for mRNA_3491 in Rhodosporidium toruloides IFO0880

Name: 11859
Annotation: K03007 RPB10, POLR2L DNA-directed RNA polymerases I, II, and III subunit RPABC5

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 74 PF01194: RNA_pol_N" amino acids 1 to 59 (59 residues), 103.6 bits, see alignment E=2.8e-34

Best Hits

Swiss-Prot: 70% identical to RPAB5_SCHPO: DNA-directed RNA polymerases I, II, and III subunit RPABC5 (rpb10) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: K03007, DNA-directed RNA polymerases I, II, and III subunit RPABC5 (inferred from 73% identity to lbc:LACBIDRAFT_190666)

Predicted SEED Role

"DNA-directed RNA polymerases I, II, and III 8.3 kDa polypeptide (EC 2.7.7.6)" in subsystem RNA polymerase I or RNA polymerase II or RNA polymerase III (EC 2.7.7.6)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.6

Use Curated BLAST to search for 2.7.7.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (74 amino acids)

>mRNA_3491 K03007 RPB10, POLR2L DNA-directed RNA polymerases I, II, and III subunit RPABC5 (Rhodosporidium toruloides IFO0880)
MIVPVRCFSCGKVVGDRWTGFLQLLEAGHSEGEALDGLGLKRYCCRRMILTHVDLIEKLL
HYNPMERRQGEGAR