Protein Info for mRNA_3718 in Rhodosporidium toruloides IFO0880

Name: 12086
Annotation: K00249 ACADM, acd acyl-CoA dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 544 transmembrane" amino acids 230 to 250 (21 residues), see Phobius details PF00173: Cyt-b5" amino acids 9 to 81 (73 residues), 73.2 bits, see alignment E=4e-24 PF02771: Acyl-CoA_dh_N" amino acids 138 to 266 (129 residues), 66.4 bits, see alignment E=9.2e-22 PF02770: Acyl-CoA_dh_M" amino acids 270 to 364 (95 residues), 72.7 bits, see alignment E=5.8e-24 PF00441: Acyl-CoA_dh_1" amino acids 376 to 531 (156 residues), 133.1 bits, see alignment E=2.4e-42 PF08028: Acyl-CoA_dh_2" amino acids 400 to 515 (116 residues), 45.7 bits, see alignment E=2e-15

Best Hits

Predicted SEED Role

"Butyryl-CoA dehydrogenase (EC 1.3.99.2)" in subsystem Acetyl-CoA fermentation to Butyrate or Anaerobic respiratory reductases or Butanol Biosynthesis or Isobutyryl-CoA to Propionyl-CoA Module or Isoleucine degradation or Valine degradation (EC 1.3.99.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.2

Use Curated BLAST to search for 1.3.99.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (544 amino acids)

>mRNA_3718 K00249 ACADM, acd acyl-CoA dehydrogenase (Rhodosporidium toruloides IFO0880)
MAQKASTFTKEQVASHTSEKDGVWIIVEGGVYDVTKFLDDHPGGKKILLNQGGKDATEKF
WSFHSKSVLEKTAKPFLIGRVGDEANQGTDVEEAVENKVEEETPGQVEEEEDTTYFGDLV
PFGDPFWYQDWASPYYKDSHRKLRSAMRAFTDEYLTPNAMAWDDARQIPPEEYKRIADFG
ILAGIAAGAGAWPTEYAQGIPVPGGFDPEEWDAFHNFIVVDEMSRCGSGGILYGLLGGFA
ISCGPILHFGSDELKKRILPPLLKGEKRSCLAITEPSGGSDVANLTATAELSDDKKHYIV
NGEKKWITNGVYADYFVTAVRTGGKGMGGLSLMVVERTEGLTTRKMDCMGVLASGTTYVA
YEDVKVPVGNLLGKENKGFQIIMSNFNGERGGIAMQANRFARVCLEESIKYANKRMTFGK
KLIDHPVIRAKLASMAQKIESTHAWLEAVVYQTTQYDHDTISLRGGGTMALLKAQSTETL
EFCAREACQIFGGLSYSKGGQGEKVERLYRDAKAFSIPGGSFEIMQDLGIRQSLKVAEIM
GAKL