Protein Info for mRNA_3806 in Rhodosporidium toruloides IFO0880

Name: 12174
Annotation: K02365 ESP1 separase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 200 400 600 800 1000 1200 1400 1600 1800 2000 2226 PF03568: Peptidase_C50" amino acids 1762 to 2160 (399 residues), 461.2 bits, see alignment E=1.7e-142

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (2226 amino acids)

>mRNA_3806 K02365 ESP1 separase (Rhodosporidium toruloides IFO0880)
MAAKPEVDAATKRPTAKLAPLGRSTAQNRVPSTSRNVEVAPTKPRSGLSRTTTQREEERE
EPVVSPTERAKEAMKVVNSALATLSGLNKAGFRAKSASGSPTAASSGVTPFASATRPGSA
ASLRATTSTSSLRTTAAHSATLTKATQAVRDCSRALKELRTLAADGILGKKKVDVERAAG
SIVANLVEMEMYRPAVVELAAMRSSLLSWWTSPPSRPTLSPSAPLASFADTLLFPLPSDA
FFAPNSLEETLDPLSARPPFADLVPLVLASQQYLLACLFRSDEEDAGSPKDKLANLAEFL
QKGTGGPLNWRRAVDCWITDEQEKAMLVKRLDAMMTSMFGTVTKGCTGVDGSAVPDDLLI
VRTHALLLYSSTSALSSANADKLSAFHDQVRKTVLLYGRAAEQARYTEVRIGNGVKEAFE
SIVAELKRRGLVEIGKDGGAKWRELCEVVLHIARRADDLAFVERISTLLGAENGSSAGPT
DVHPDLLSSQICAKLASVLSVFEIWVKTSGADDRGVVDQMRRLSGLLPVLTKLRCAATAE
GGRAPSNDSKTKIDKTVDRLRYVFAKHVKAGKRMDQLLTPADAIPPPVDEVTVLAKVALD
RLAHHAEQILAANAIEGKNRSYLAATTVDTLLLLAYSSLIVDDRSTALPCLAFLERCLPL
VGFSPSTILALDLHYSIRTLTSACYNIGGTLFNAARPELAVNFVQRACDLSAKVLDQARS
DDLLPSSSGADHDELSSQLDSLKLATGEVGKEEKELREAQQDFERLMSRRWELLAMTRYA
MGDKRAAYDAYVAAVHAQPSAVFAPLATAASRQSLSEILSTHHSLYKQVERLTRLSTYDL
LLPPALVPLSSSPTLSSTLSRDVRGVLLEMQLAVLEAQTDSREGRCAAAALLEQLLAIYH
ADETPVRRARVLVKSLQHSCAGRDRDSETHARALADEIANLCAKENLQDDDALRPLAAQY
NALSHLFLAFRLQAIRTASADASDAIASEARQALQVLRGVLDGDSKCATHRPSNSPRRSR
QTAASPAKPTSPPQPTPAPTRRRPARIAASAATPARSRLGRSQRGAAPASTSPQVTPPRR
TSVAVDLRESTRTPAPKKLVPSGVDKLVALDGADSVYKSFESMASLLGVLGQALLKIGYL
KFLRQLAERLEEGGNAYVIASITLAREYLRLGKTSRAGLVLAQAESRVQSAARDEQPVAV
DAHVSYLLVNAEYLATAQAYEAALSLADELASATAASATARVVERTLLLQRASMAAITCS
YLLQRKASLLFAEGELSRALPPAIQAMRLATRAVNNLSRLASSPKPATPSAAESTFTAPL
TDHVTPLADAPPINERKTSTTIPSGIHAGLSWRLLELLLATIERVALVHFVRGTPKSADY
FAQQALDFAEDVGSANGMARALLLRADVRLQWGKQAEAAADLDRVSQLLRSSSTPEAAEL
LRLQGDLHLRENMRREAQELYLDANRVLDTFIASASDGDAGQSPVKHHTPVQNGSAGRRR
VSGPSVHFAHLSPSPIASKASPAGDWVLPAVQCRLLRMQAHLLAPQSKNDELTRLLRRIA
RLASHEEEKADELRLVVALKLRELLARFLSLPVFGISATGAAPKVGTPRTGPTVVNIVKD
IDNLLARAVNFSVSRASAKKVRELSLLSASVRAMQASVGKSTKRSTATIAHLLDLGVAVS
LRREMAEAVEQRLDRAIRRDDMTWPSLDLAPVPTSEDIDEHLLKTRDRYRLEAAEPILTE
QSISTLLSPAWSVLTLHLTPEHDALIISRHRHADEPIVFKLPLDRLARREGEEEDAFTFD
VAMIELQDIVERNNTGAQNAKLVDGKEQRAAWWAERKELDQRLGDLLQTVEDAWLGAFKS
VFYDARLHSGEAFASFRSRIERILKRSIVRAAGDQRATRFKLDDAILECLAALPATSREE
DLEDMFYYMAESFQFSGVPLASDETDVDQVVVDLREALEELHGTKSAPKSKASPDEHTFL
ILDKRLQAFPWESLPCIRGRSVSRLPSLSFLRDRLDLAADRSPETPHDFVVDHARTSYLI
NPGGDLKNTQQTFEPWLREQADRHGWTGVVARTPLEEEVKQGLTSKELFLFFGHGGAEQY
IRSQTIRQLPRCAVTMLWGCSSGMLKDQGDFDPVGTPYHYMVGGCPSLVANLWDVTDKDI
DKFAFSVFRKTGIAEPETASPPPSPPLSLTAAVAQSRDVCNLRYLNGAAPVVYGIPVRFA
LSQSQV