Protein Info for mRNA_3950 in Rhodosporidium toruloides IFO0880

Name: 12318
Annotation: K03456 PPP2R1 serine/threonine-protein phosphatase 2A regulatory subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 607 PF13646: HEAT_2" amino acids 362 to 463 (102 residues), 43.3 bits, see alignment E=1e-14

Best Hits

Swiss-Prot: 54% identical to 2AAB_PIG: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (Fragment) (PPP2R1B) from Sus scrofa

KEGG orthology group: K03456, protein phosphatase 2 (formerly 2A), regulatory subunit A (inferred from 70% identity to uma:UM02960.1)

MetaCyc: 56% identical to serine/threonine-protein phosphatase 2A regulatory subunit (Homo sapiens)
Phosphoprotein phosphatase. [EC: 3.1.3.16]

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.16

Use Curated BLAST to search for 3.1.3.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (607 amino acids)

>mRNA_3950 K03456 PPP2R1 serine/threonine-protein phosphatase 2A regulatory subunit A (Rhodosporidium toruloides IFO0880)
MSNWQSDPLHPIAVLLDELRAEDVALRLNAIHRISTICLALGAERTRTELIPFLQESLDD
DDEILLALAEELGGTFVEYVGGPDYAHLVLPILEHLAGVEETLVRDKAAQSANQICDVLS
QEQVEEHFVPLVRRLSTGEWFTSRTSATALYAAAYPKATPPVQEESIRMYSKLCEDDTPM
VRRAAAKELGGFSKQLGHDNLVNSLLPAFRKLSSDDQDSVRLLTVESMISIAEQLSEDEC
KNLLGQTMKSLVNDRSWRVRYMVADHFVKLAKAAGEDIVRDELVAAYVALLKDQEAEVRT
AAAGQIPGFAELVDRDTILNRLMSCIRDLSTDASQHVRAALASQISGLAPLLGNDATIEH
LLPLFLQLLKDEFPEVRLNIISKLEVVNNVIGIELLSKALLPAIVELAEDKQWRVRQAII
EYIPLLAKQLGVAFFDEQLANLCMGWLGDPVFSIREAATINLRKLTEVFGVDWAKETIIP
RVMEMGHNVNYLYRMTTVFAITTMAPALDIDSIRSSILPTVVSLSTDRIPNIRFNVAKAF
EVLSQSLASQQGGPDLVSSEILPALDKLRSDTDADVRFFAEKASEKAREVASGEAQAVSE
EVVMTDA