Protein Info for mRNA_4016 in Rhodosporidium toruloides IFO0880

Name: 12384
Annotation: K01250 rihA pyrimidine-specific ribonucleoside hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01156: IU_nuc_hydro
  • amino acids 6 to 358 (353 residues), 289.6 bits, E=1.9e-90

Predicted SEED Role

"Inosine-uridine preferring nucleoside hydrolase (EC 3.2.2.1)" in subsystem Purine conversions or Queuosine-Archaeosine Biosynthesis (EC 3.2.2.1)

MetaCyc Pathways

• purine nucleotides degradation I (plants) (11/12 steps found)
• adenosine nucleotides degradation I (8/8 steps found)
• guanosine nucleotides degradation II (4/4 steps found)
• superpathway of purines degradation in plants (14/18 steps found)
• superpathway of guanosine nucleotides degradation (plants) (5/6 steps found)
• adenine and adenosine salvage II (2/2 steps found)
• guanine and guanosine salvage II (2/2 steps found)
• guanosine nucleotides degradation I (3/4 steps found)

KEGG Metabolic Maps

• Nicotinate and nicotinamide metabolism
• Purine metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.2.2.1

Use Curated BLAST to search for 3.2.2.1

Protein Sequence (376 amino acids)

>mRNA_4016 K01250 rihA pyrimidine-specific ribonucleoside hydrolase (Rhodosporidium toruloides IFO0880)
MPACIPIWLDCDPGHDDAVAILMALHLPEIDLLGISTVHGNASLFNTSRNAARCLLAFGS
SEQAKRIPVYAGAEKPLLRYIRHDSEIHGEDGLGGVEGLPPSDSPAVLSKLDETKGKNAV
VALADAARSLPDGEQLTIVATGSFTNVALFVSLFPELVRDKVEKVVVMGGAEGRGNRSPT
AEFNVLCDPHAASILLDAEVPVVMAPLNITHTAIFRKDDNSTLLVPPSAIPDLASSTPDA
TAHPSRAHTPLRHTLHTLLNFFASTYKSVFSFDDGPPVHDALCIAYLARPEIFKAKRYRV
DVETEGTHTQGTTVVDLYDYKKDQLVEFKKDPESRASWGRFGKNVLMLEELDVPEFWRMF
QQCVDEADKVSPLNSK