Protein Info for mRNA_4037 in Rhodosporidium toruloides IFO0880

Name: 12405
Annotation: K12232 HECTD2 E3 ubiquitin-protein ligase HECTD2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1195 transmembrane" amino acids 338 to 357 (20 residues), see Phobius details amino acids 383 to 401 (19 residues), see Phobius details amino acids 813 to 834 (22 residues), see Phobius details amino acids 846 to 873 (28 residues), see Phobius details amino acids 952 to 972 (21 residues), see Phobius details amino acids 1062 to 1085 (24 residues), see Phobius details PF00632: HECT" amino acids 479 to 774 (296 residues), 256.4 bits, see alignment E=4.5e-80 PF01529: DHHC" amino acids 915 to 1088 (174 residues), 55.9 bits, see alignment E=5.3e-19

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1195 amino acids)

>mRNA_4037 K12232 HECTD2 E3 ubiquitin-protein ligase HECTD2 (Rhodosporidium toruloides IFO0880)
MAERLVLLLDWGRRTANPQHSTRSAIQGPVKHPCRAATLPSPLLSDIIASFSLACAVSTS
PAYRGCLLLLWDGAEVPTVEPELSMYDLRNRQRSFGGGKERKDECGCVPVPEAIPVTEDE
VLRTIEQLEARQKGGEEDLVGRLGTVGLSDSRQHASDEDDPEDLLLAQLATAFTNLPSLD
ASFRPTRSTSVSNLPQQSTLARLYKLVKLRPAALEVLRDQVDAILRRPGSTLAEGDGGWV
ITLVECPIFLADFTVEAETRRSLQSRLIGLLSNLPNSMHHSLVTYLSSPTYPRSALLEEV
ELVCGFISFRIGQCIDGDQPEAYVDDWMVRAGARVASLLFAANLNAQLLPLSAFYVTLID
SLGESILITDFQAWENRISRFSLCQYPFLLSLGVKMMLLAFDGERQMIERTREAYRNNLS
SEEAENPLLVLRVRRDRLVDDSLRQISLHRTDLKKPLRITWEGEEGIDAGGLRKEWFLLL
CRQLFDPQFGMFLHDPDSNLCWFNPAAIGMEDDFWMVGVIVGLAVYNEATLDVPLPLATY
KKLASESLTLRDLAQVQPSLARGLQQLLDYDKGDVEGTFMRSYVGTYEAWGELVEVELVE
GGAEIAVTEENRQDYVQRFVDFILSTSVSSQWDAFAEGFIEVCAGNALSLFKAQELELVV
RGSPEPLDVGALKGVTVYEGFSPDEPTIQYFWSVFASLQPDRQRRLLAFCTASDRVPATG
VSGLQLRLQCLGDDNDRLPQSHTCFNTLSMWRYGTREKVERMLVRVMEDTRSGFPSTTHS
QDHREMRAPVAGTPGCGTSPVPLRTQRWKRPNVWLGAIIPSLLLVFALKGYSLVLLEIIP
LFWSRYQAIACGYAIVVHIALFLTGYSYFVVFFQSRDSPERKEPPVEVQEKLVVFACDEQ
GEPIRCGRDSCGGAWQSLRTRHCADCATCRPNFDHHCAFVSNCIAQDTMKPFFTFLVWAA
ILLSVALVPFVPLEYRSVREVVRTTWDTVELKEQWWSRKLSWAGGPVWRYAGGLLLGYRL
YQKTAHERPLLVPDVTTRTFTQGGITYAYDVPLYPSLAVPHLGTLAVVFFALFITLIALA
MIYVIARNTRLGTSAIQIERTRLWRSQDGGKPVYDTRVALWVPLEADDKAKRGAVVFVEP
DTPLFDLGPSENWRRVMGEKWWQWFVPWVPSRASDLHDLNPQVVEALRERARKKR