Protein Info for mRNA_4038 in Rhodosporidium toruloides IFO0880

Name: 12406
Annotation: K10772 APEX2 AP endonuclease 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 613 TIGR00633: exodeoxyribonuclease III (xth)" amino acids 1 to 299 (299 residues), 142.8 bits, see alignment E=6.9e-46 PF03372: Exo_endo_phos" amino acids 4 to 292 (289 residues), 58 bits, see alignment E=1.1e-19 PF06839: zf-GRF" amino acids 536 to 594 (59 residues), 33.1 bits, see alignment 4.8e-12

Best Hits

Predicted SEED Role

"Exodeoxyribonuclease III (EC 3.1.11.2)" in subsystem DNA repair, bacterial (EC 3.1.11.2)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.2

Use Curated BLAST to search for 3.1.11.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (613 amino acids)

>mRNA_4038 K10772 APEX2 AP endonuclease 2 (Rhodosporidium toruloides IFO0880)
MRIVTWNVNGIKTLLQYHPWNQKRTYEGIIEDLGGDITCIQETKITRAQMERGMAVLDAY
DSFFSFYRRSVRGIHGTAIFTKRDVVVPVKAEEGIASSLIPSTMAVADRIGGYPLSSEAD
LDYNAMKDLDSEGRTTVIDTGMFVLINLYCPNETNSDRLVFKNNFNTLVDRRVRNLIKLG
REVIVVGDLNICASDLDTAEPEQRARDSGLENFTDHPPRAWLGAFTGPNGPMIDITRRLH
PDRQGMFTCWNTKIEARVSNYGTRLDYILITPGLLPWVKFSDIQPKIVGSDHCPVYLDMY
DELDIPGRGKVSIWDELNPGRKKGDRLPDPPAFASRFFSEFSGKQKLLSNFFAKKSEMPP
DAPKPSPSPSPQPNSASTSASTSKNSSLSTMASITSITNGSSKKGKGKEKSPEEEKPKTG
QQGLSSFFKPPPTPEARPTKKRKKSQTDPTPPPPSNSRPSTSRSSSSSQTKPSPSPTASF
RNGDGTEVLVLSDGDDDAEEELDLKEREDATADPGFNPNAQSASAWSSIFASKPVPLCEG
HSEPSRVWTVNKPGPNKGRRFYLCARPVGPGYDQGQSKIHVNPEYRCNFFQWETKVKRPA
GMVLSSSAKKQKT