Protein Info for mRNA_4063 in Rhodosporidium toruloides IFO0880

Name: 12431
Annotation: K10777 LIG4, DNL4 DNA ligase 4

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1116 PF04675: DNA_ligase_A_N" amino acids 51 to 251 (201 residues), 148.9 bits, see alignment E=4.9e-47 TIGR00574: DNA ligase I, ATP-dependent (dnl1)" amino acids 113 to 663 (551 residues), 327.9 bits, see alignment E=6e-102 PF01068: DNA_ligase_A_M" amino acids 293 to 525 (233 residues), 146.4 bits, see alignment E=2.3e-46 PF09414: RNA_ligase" amino acids 331 to 525 (195 residues), 43.6 bits, see alignment E=1e-14 PF04679: DNA_ligase_A_C" amino acids 550 to 661 (112 residues), 44.4 bits, see alignment E=5.3e-15

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1116 amino acids)

>mRNA_4063 K10777 LIG4, DNL4 DNA ligase 4 (Rhodosporidium toruloides IFO0880)
MAGTVQWRGREPRANRPKRSDDEDEVDDNLQFAESDDIEKPPGLENGPTPPFGVLCMLFD
QFESATRNKHKKVGYKGELLGQFISHWRAEIGPDLYPLIRLMLPERDTRRRTYNLKEQKL
AKAIIQALDLPQKTSVALKLINWKVPTKEDPGAGEFAAVAYDVIKSRSTVIRAVSDVTID
EINETLDELSHTRGTTIDANGQKRGMQAEHARILRRCVSKMTPAEMKWLIRIILRDLKIG
MGEKTIFNQLHPDAMDLFNTCSDIKRVCYKLFDPHQRIPHEDHTVKINQVFRPMLCWRTQ
RSLSDVIKAMRRNRSAQDPNRPLEEGEYAKDEFIIEEKLDGERIQLHKKGDVYLYASRKS
KDYTYLYGADASTGSLTPFIQDCLNENIEEIILDGEMLVWDPKIGKYMAFGNLKTFASNE
MKHFGPNDPRPCFKVFDILYIKGKGGKATPLIEKSLWRRKHLLGQVITQKQGVMEIADCA
RGSSIDDIREYLQRILEERGEGLVCKHPLSTYVLGGRMDSWVKIKPDYMDELGEKIDGLI
VGGYWGQGSRGGRLASFLVGLRGTKNGKEVYKSFAKVGSGLSRADYTWIVENTRGKWIDF
DRRDSKSVPDWFETVTEWPDVLIDPADSFIIEIKAAEIVEGAEYGAGMTLRFPRASKIRD
ELDPLSDSMDFETVLAFRRAPKKRPFGDDLASKSKAIRINRNGKARAVSSAVGDVEQTSD
VFEDVIFCALGNLAAHRSNRVYLSPRADIHQTKPPELKEQLQKKVVEAGGNYIQTIPPAD
IERVVVASEYAGIKNKKGGKEVDIVTPEWVLKSIERKRRLPLHKRYLVHAMPKTMSSPDY
EADSDNEGMQVEGSEDVKPDVSQGAPRRITAAEAWSQYRGEVAADDEDDPETEDDEGELL
AVKTEDAPLPEVPQYEDYWPRKGTMAPPVNAINQDVGKLDLGTSSSQEKKPDADSFGGRV
EDLQLGAGESSARSETVAADNDGLTDAPPGMGAGADDQKAFDPDRPLAPFVAYFDTRAGA
EKNDLPSSKASDRVQTVADSQLAKAKTAFEEAGGIATDDLHNPKLTHIIITKLVPDRYKE
LINRTAEPRYRRIVTTEWIDACIEEEGPMDEDDFKP