Protein Info for mRNA_4066 in Rhodosporidium toruloides IFO0880

Name: 12434
Annotation: K03426 E3.6.1.22, NUDT12, nudC NAD+ diphosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF09296: NUDIX-like
  • amino acids 32 to 209 (178 residues), 55.7 bits, E=6.8e-19
• PF00293: NUDIX
  • amino acids 268 to 374 (107 residues), 54.4 bits, E=1.4e-18

Predicted SEED Role

"NADH pyrophosphatase (EC 3.6.1.22)" in subsystem Nudix proteins (nucleoside triphosphate hydrolases) (EC 3.6.1.22)

MetaCyc Pathways

• NAD salvage pathway I (PNC VI cycle) (6/7 steps found)
• NAD salvage pathway II (PNC IV cycle) (4/5 steps found)
• NAD salvage pathway III (to nicotinamide riboside) (2/3 steps found)
• NAD salvage (plants) (6/11 steps found)

KEGG Metabolic Maps

• Nicotinate and nicotinamide metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.22

Protein Sequence (450 amino acids)

>mRNA_4066 K03426 E3.6.1.22, NUDT12, nudC NAD+ diphosphatase (Rhodosporidium toruloides IFO0880)
MENYYAGNPLNRLSYLRSSQAFLTSALRSPKAKFLPLDSLSPLCKHDKDGARHLHFVGWK
DVEAVVGEAEQVFAGVDGKRDEDVPELAILGLQAKRLGKTRVGDLSHDEKMRYFLDQPAL
VFLGVDERSAPESAKSLPVSKPDEHSTLETHSPYGEPYWALDVSALPDLKQKILQENEGA
KFMELRSGAQTMPTQEASIAAEARALVDWNTRNKFCPACARPIRSVWAGWKRSCIPGEPS
ADGVDGQATACISRKGVHNFSYPRTDPVVIMAVLSPDGEKILLGRQRTWPARFYSCLAGF
LEAGESLEEAVRREVYEEAGIVVGDVGYHSSQPWPFPASLMFGCWGVAKTEDIRVDLDNE
LEDARFFTRDQVLKVIQSTKPMQLSREQVARIDGKEGAASDKHDLADAKKKADDEGSFLM
PPATAIANTLVTAWATGKLFNQVPVSVSKM