Protein Info for mRNA_4072 in Rhodosporidium toruloides IFO0880
Name: 12440
Annotation: K16575 ACTR1, ARP1 centractin
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 73% identical to ACTZ_PNECA: Actin-2 from Pneumocystis carinii
KEGG orthology group: None (inferred from 82% identity to lbc:LACBIDRAFT_300668)Predicted SEED Role
"Adenylate kinase (EC 2.7.4.3)" in subsystem Purine conversions (EC 2.7.4.3)
MetaCyc Pathways
- superpathway of purine nucleotides de novo biosynthesis I (21/21 steps found)
- superpathway of histidine, purine, and pyrimidine biosynthesis (38/46 steps found)
- superpathway of purine nucleotide salvage (14/14 steps found)
- superpathway of purine nucleotides de novo biosynthesis II (21/26 steps found)
- superpathway of adenosine nucleotides de novo biosynthesis I (5/5 steps found)
- superpathway of adenosine nucleotides de novo biosynthesis II (6/7 steps found)
- adenosine ribonucleotides de novo biosynthesis (3/3 steps found)
- purine deoxyribonucleosides salvage (4/6 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.7.4.3
Use Curated BLAST to search for 2.7.4.3
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (373 amino acids)
>mRNA_4072 K16575 ACTR1, ARP1 centractin (Rhodosporidium toruloides IFO0880) MDSLNQPIVIDQGSGTLKAGFAGSDHPSTYFPSYVGRPKHTRVMAGAVEGDTFVGRKAQE LRGLLRINYPMEHGIVTDWDDMERIWSHVYTEELRTLSEEHPVLLTEAPLNPNSNREQAA QIFFETFNVPAMYMSVQAILALYASGRTTGIVLDSGDGVTHAVPVFEGFAIQHAIRRVDV AGRDVTDHLQLLLRKAGYHLHTSAEKEVVRMIKEKTCYVALSPAKEEKEAQAGGKSEDFR LPDGNVIRLGPERHRAPEVLFNPEIVGLEYAAVHQVVVDSINRADLDLRKSLFGNVVLSG GGTLVKGFGDRLLHEVKKLALRDTKIRISAPPERKYSTWIGGSILAGLSTFKRMWVSAEE YQEDPDIIFKKFA