Protein Info for mRNA_4168 in Rhodosporidium toruloides IFO0880

Name: 12536
Annotation: K09487 HSP90B, TRA1 heat shock protein 90kDa beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 682 PF02518: HATPase_c" amino acids 23 to 174 (152 residues), 32 bits, see alignment E=2.4e-11 PF13589: HATPase_c_3" amino acids 24 to 146 (123 residues), 38.4 bits, see alignment E=1.7e-13 PF00183: HSP90" amino acids 178 to 671 (494 residues), 460 bits, see alignment E=2e-141

Best Hits

Swiss-Prot: 40% identical to HSP80_SOLLC: Heat shock cognate protein 80 (HSC80) from Solanum lycopersicum

KEGG orthology group: None (inferred from 48% identity to cne:CNE01170)

Predicted SEED Role

"Chaperone protein HtpG" in subsystem Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (682 amino acids)

>mRNA_4168 K09487 HSP90B, TRA1 heat shock protein 90kDa beta (Rhodosporidium toruloides IFO0880)
QSDIARLMRVVVSHLYHDRDVFVRELLSNANDALEKVRLIALTDPSILEPAEQLNVTVLA
DKDSGRIVIRDSGIGMSKEQLAANLGTIARSGTSEFLENLEKGDGGNLIGQFGLGFYSSF
LVADRVTVASKTADDVEQWVFESEANADGFKIVKDPRGPTLGRGTEITLYLKPDAADEYL
DLPKLRSLIQKHAEYNAAPIYLWTSASLDPSVNAVPVVEAEDDEIKVEDEATAVEQPKWD
LVNDRPPLWMRDSKDVTEEEYENFYMTTFDSPDAPLAWAHFKGDAGSTSFRALVYIPSAL
PNDFYSKDYISLNSLKLFVKRVFITSDLGPNYLERHMNWIKVFIDVDDLPLNVGRDSLQK
TKALAQIKKNLQKRVYDLFAQIASQDPTKYAELYEKAGVALKVGVVEDAKNRDRIVKLLR
FTTSAQENSTSLDEVVARRKQGQTQIYYIAGAGQKKESLEKSPFVERILARGYEVLYFTD
PIDEMVINSVPTYGGLRFQDVAKDGVKFGDEDDDEKKEEEDLKSTFAPLVGYLKKELAEF
VDKVTISTRLTTSPCLVTAGTYGYSGNMERLLAAQNQGSDNFMLNFARMQKKNFELNPKH
PLIERLLEKVDEAGDDEDALAELKESVSVLWQTALLKSSYQVPDPNSYFSLVESMLRKSL
GVSQTAQAEVDVKPAPPVETGP