Protein Info for mRNA_4174 in Rhodosporidium toruloides IFO0880

Name: 12542
Annotation: KOG4305 RhoGEF GTPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1387 transmembrane" amino acids 1033 to 1054 (22 residues), see Phobius details amino acids 1066 to 1087 (22 residues), see Phobius details PF00621: RhoGEF" amino acids 623 to 800 (178 residues), 99.8 bits, see alignment E=2.4e-32 PF00780: CNH" amino acids 1042 to 1331 (290 residues), 161.2 bits, see alignment E=4.2e-51

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1387 amino acids)

>mRNA_4174 KOG4305 RhoGEF GTPase (Rhodosporidium toruloides IFO0880)
MAQEYSYFAGEQPQRQRPLPPPPPFARTPTSTVHEGQGTLYETGPQSGYSYASYPPQPSS
SASFRDIASAPKSRPYPSYTPASHAPAPPFDPSPGGAYAAPSPPPGAQPPVFTRPATYAS
YQSSSRVDPEWRESSFISSYGGFSSPPEPAGPSNGSYFAASSVPTVVPTGAQPPYSAYTS
SPRPRTSEPPELPPLNLRDHPARLSDDSAQYSLYSLPSDLSPTTSRPLADKPPRPNELSA
TAHAQVTPPPRSSSSAGSYTRSARRDHTFAYQQWTAEGDGLPSQLALDSLSLQSAATTSA
GSTTNQHSPPPRPPRPPAPRQPTILTSPPLETSAVPVHRSHSTNSTWSRAISSPSIPSFT
ASPSPDISHRPSYATLSPNTSLYASSSFPRADSYEGSGHGSPALNTDGVGAFGGGRPQYL
NAALLSDLAVYVKDHVARGPRQKGSIEHYGFTGEDVVSAIRQALPSPANFDRRLALAIAR
SMQQALWFHEVDWSDSPLRDAPGGHVYAFLEDEIRDGRGASPDDLAGGRHDDPAAELPTG
VFVDLTRCYSPYCGQFSTSGYHGACYSYTCPNRRNTGLSRVGSTLSAISAVEIVEEADNW
ATSVPKSLLDSLSQSEIAYQNQVFELIQGEQKYFEDLQFIETGFVEPLRSAKPPIIPPER
LESFLSSVLLNVSEIREHSQAFLLKLRKKQQEGHVVRGIGQIVLAAAVEWGPAYLHFTTN
FPMADFLFKEEKAANPRFEELLMDFHKRPEASKRGFDTFHNRATFRGLRYILLLEQILKN
TPEGDPDREHLSQAVQVIRQQGADANAGIDATKSRVALKEFGRDLVAKSGTTLDLELSDT
SRRFFMAGRIYRRPEGSTFADQFQDGHLILFDNYLVFTKTPRPDRSGHQKYQITRRPVPL
DLVQLKTTSFAEPPIPRSSGFHLRSTRSTGIAQATPQPAADGTQLLYPVSYFQLGRFDGL
VYFYVDSAGVRDEWEKMLKEAVTQRLRQQELRRVVRLDPLADQTFGTTSTIGSLSGASGA
PNQFGRPTCSTPLMTVDGLWLIIAGCAEGIFVGWRGRPKTMQQVVHLAGITQCAVLTEFS
FLLVIANKVLVAYALEALIPSSTGTKLDQASKAPQRLSGQKDVSFFKVGKIGGEADSRTL
VIYAKKSGVKESVFKALEPVGQDERKRTGGGGRFLGLGSGRPEWFRTYTEFFMPSLVTGL
YFQRSKLALIGSRGIEIMDLDSMRTMTVPDFPASRQDRAALLLAKRCEDASTLGMFRIAE
SKFLLAYTEFAFHVGRHGEPVEGPFMEWESKPEQVAYCAPYIFAISPTIVEIRHAFTGRL
VQFITGAHISLTYDGTAIVSAPPQSHFSPGVGSGSPSSDLVLPPDRRLHLSMRQGTFHVL
YEVVIVA