Protein Info for mRNA_4275 in Rhodosporidium toruloides IFO0880

Name: 12643
Annotation: HMMPfam-RhoGEF domain-PF00621,ProSiteProfiles-Dbl homology (DH) domain profile.-PS50010,SUPERFAMILY--SSF48065

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 817 PF00621: RhoGEF" amino acids 429 to 541 (113 residues), 29.8 bits, see alignment E=3.6e-11

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (817 amino acids)

>mRNA_4275 HMMPfam-RhoGEF domain-PF00621,ProSiteProfiles-Dbl homology (DH) domain profile.-PS50010,SUPERFAMILY--SSF48065 (Rhodosporidium toruloides IFO0880)
MFKFWKSKNKSPKQPAQPDKSPSPAPLDHPNRPSTPSHALHGLGLSVPPRKGTSTSSRRD
FGSSTAPSFDSSRLSPEPLAAGSSGGHGDETGWNGSGGHEKSRRGSDQSAYSNVLREKSV
NVLDFGRKAYPEGLKVPYGRSDRAVSPASFATTASMMHSRYPTPYGAENGGFPDNDPTQI
HAPTTWSEMAHQELVANLSPRERTRQEILWEVVASEERYVAELRSLVDLYAHPLLHPLLS
NSPSPHTSPNLSLSPTISSPSPQLSASPSPDLPIASRFSRSTLRLSSPTPEDENDLSEIS
HGPSTSGALSLSPIPSLPTGARQNASHTSLDVPGARSLADRVASFGSRTRHPLRPEPSAT
KLHKSASKAPPEVLQPPPLPDALKQVLEATVEMLKGHEELSARVKEQWARAFPLVRGLAA
IWSDQPWFLQTYASYIVALEEALAILDTCLPSPHSPSLSSYASRFKSPKTPAEKETKRLA
RALMRLEEQAAAAGESSLSICLSKPLMRLSKLPLLMQALLYHTDPTTHEWEKTRAMALEV
DALVRSIEDEKLEEEEREKTRDALARIDGIRDKALMAPRSARILIEEVPAPDARTRRRLS
APTARRGKNEWLIRFTDVVIRAEKTGETDIPGSFSRQKEKKGKQGKPRKNGKLRNTYRFV
SVERWEPREMADLALHDLNELRRLKNEGSAPPSEDGEMTDSIAESRMSFRYDTDEPQPVR
RDFTSLRSPPSAPSAKFGHRLRIGSEGPPGARSPTPNQNQHRYDSPTVSSALKAQPARPL
VPAQNGVKQEPQAGRSLAHARDDSTFALYSIWSSAQE