Protein Info for mRNA_4363 in Rhodosporidium toruloides IFO0880

Name: 12731
Annotation: K19562 BIO3-BIO1 bifunctional dethiobiotin synthetase / adenosylmethionine---8-amino-7-oxononanoate aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 852 transmembrane" amino acids 554 to 571 (18 residues), see Phobius details PF13500: AAA_26" amino acids 8 to 201 (194 residues), 60.4 bits, see alignment E=2.2e-20 PF00202: Aminotran_3" amino acids 353 to 587 (235 residues), 78.4 bits, see alignment E=4.5e-26 amino acids 617 to 709 (93 residues), 49.3 bits, see alignment E=3.1e-17

Best Hits

Predicted SEED Role

"Dethiobiotin synthetase (EC 6.3.3.3) / Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)" in subsystem Biotin biosynthesis (EC 2.6.1.62, EC 6.3.3.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.62 or 6.3.3.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (852 amino acids)

>mRNA_4363 K19562 BIO3-BIO1 bifunctional dethiobiotin synthetase / adenosylmethionine---8-amino-7-oxononanoate aminotransferase (Rhodosporidium toruloides IFO0880)
MLSRHLRTHLIVAPSTSVGKSIFSTGLVRASLALGEKVAYLKPVGTGSGDGDDELHLQRF
APQAKTACLFHFDEPVSPHLAVERSAAGLSKAVTKAPTDAEFAAAVGKYARSFAEETAGK
RSSLYIETAGGVHSPTLCGTSQLDAFRPLLPPTLLVASAALGGISTTISAYESLMLRGYD
VDAVLVFREEYYANYQYFEKWFTERGIRVGVVDQPPEQVTNAAEDAANLEAYYSKLAGSP
LQRIVQRLQQIHLDRMSNLATAPRRTLDKVWWPFVQHGLVQNESDVMVIDSAHGDHFSVF
ATSSPPVEPPTPSSDPSAAPVVPPSQQATSTTAATPSSPPAQSPAHPLLSPVFDGSASWW
TQCLGHANPELTLAAAHASGRFGHVMFPTATNLPALELAEKLLATVGEGWADRVFFSDDG
STGMEVALKMALRAYADRERLSPAEGRRLAVLGLKGSYHGDTIGAMDACEGGVYSERVEW
YEGRGYWLAAPEVRIEQGKVVVRGKGGRATSYDSLTQLYDVDRRVRDDELARVYREEIEG
ELQKRLDKGDGIRFGALVLEPVVMGAGGMIFVDPLYQRVLIDVVRTNRQLFPAASPAPSD
SATLAATGSTPVWQGLPVIFDEVFVGLHRLGRTTASTFLGSSTKPDIACYAKILTGGLVP
MAVTLASDAIFRAFWSDKKVDALLHGHSYTAHAVGCGVANKTLAILDRMEKQGVYDGAKQ
DWATAASSAEGGAASGVWSLWSSSFVQSVSSHPAVDGVMAIGTVLAIHLKAGDGAGYQST
ASETVLRQLRFGAPFDSDPAAAASPSGAPFHIHARPLGNVIYFMSSLNSSAETLRSVEGS
IVAALDAKAGAS