Protein Info for mRNA_4372 in Rhodosporidium toruloides IFO0880

Name: 12740
Annotation: KOG2533 Permease of the major facilitator superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 508 transmembrane" amino acids 29 to 46 (18 residues), see Phobius details amino acids 68 to 91 (24 residues), see Phobius details amino acids 97 to 117 (21 residues), see Phobius details amino acids 123 to 145 (23 residues), see Phobius details amino acids 157 to 178 (22 residues), see Phobius details amino acids 191 to 213 (23 residues), see Phobius details amino acids 264 to 286 (23 residues), see Phobius details amino acids 311 to 329 (19 residues), see Phobius details amino acids 337 to 358 (22 residues), see Phobius details amino acids 369 to 391 (23 residues), see Phobius details amino acids 403 to 425 (23 residues), see Phobius details amino acids 437 to 457 (21 residues), see Phobius details PF07690: MFS_1" amino acids 35 to 397 (363 residues), 95 bits, see alignment E=2.4e-31

Best Hits

KEGG orthology group: K03448, MFS transporter, ACS family, pantothenate transporter (inferred from 41% identity to ure:UREG_07875)

Predicted SEED Role

"Nitrate/nitrite transporter" in subsystem Nitrate and nitrite ammonification

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (508 amino acids)

>mRNA_4372 KOG2533 Permease of the major facilitator superfamily (Rhodosporidium toruloides IFO0880)
MGWLSRTRSLVWPEPRDPLERSLLRKADALILSYLCLNFCINYLDRVNFINAYVSGLGTA
LHMKGREYNAVIACFTAGFAIAQIPQNLLLLLIPPRYLFPLNGVVWGVLTAAGAGATKVQ
HLYVIKFFQGMAECSTFIGAHYILGSWYHPSEIGRRAALFSASAQIASIFSGSLQSALYT
NLDGACGLEGWQWLFIVCGIITVPIALFGIYSFPDTPTRTTSRLFTPQERALAIARLPPP
SRAQKRGVGVDWTLVRRVLSRWELWGLALVWIAGGALESYSSWGIMPLWMKAQRTSQGKA
RYSVAELNHHPLGMPAVAIAALLVTAIWTDRRTKDRYAVNLVVALAVLVSSLIVLISGLK
PVGSVPRGAVYFAFYLSAVSFAGQMSNFAWANELLRDDEEARSVVLAGMNVISYAFNAWF
QIAFFPASSAPRFTRGSSLMIAFCPLLAVFTGVVRGLQVRTERRRALNVVVEEGKEEKAE
EKEGEGKRPGTGTTVVGDGEGEGKDMER