Protein Info for mRNA_4419 in Rhodosporidium toruloides IFO0880

Name: 12787
Annotation: K11121 SIR2 NAD-dependent histone deacetylase SIR2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 711 PF02146: SIR2" amino acids 79 to 181 (103 residues), 77.8 bits, see alignment E=5.3e-26 amino acids 247 to 351 (105 residues), 41 bits, see alignment E=1e-14

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (711 amino acids)

>mRNA_4419 K11121 SIR2 NAD-dependent histone deacetylase SIR2 (Rhodosporidium toruloides IFO0880)
MATPPLPVLSFGDGPPPSLSDLPPFPTILLPQCAVSGARAKPSGSSGVSSASSSASSNID
LAHVARTVLKAKRVAVVCGAGISTASGIPDFRSGAGLFKSLKEQHPDAKLTSGKDLFDVG
LFSSEANAAIFYNMIAELKKQTDAVEPTAFHSWLKDLDDEGKLFRVYTQNIDCLEEKAGL
TYGLGDKSLPLPPRRAGRSPSKARPSGNSTPTSVALQPSSSQASTASTSYPTPRSSASPP
PTHSTIPRVIPLHGHLATLSCSACKLTTPVDPYLDLLASGSAPACPSCLSIDQARSAAGE
RSRGVGMLRPDVVLYGEEHKDGERVGEITQRDLMGQRPDLLLVVGTTLKVKGTKRLVREL
SKVIKPPSKSASTTEQDDEPPSSSPAFPSSSQQSATSKRPRQNRPPPIHTLYLNYDFPTP
SREWAGVFDCWLRGDIQQFVQAVKDEKERMKVEMEEKEQRKRKREEASSTPRKARAAFSG
MGKEPERPKGRTTMAAMRASLPMGGIQRPPASTHALPVDIPRLFGLPPNTALPPLPVTAP
PAPPPKPVAATSISASSFLASPGATVVRPFSTMPSAVAAAPAPIIPASPASSAGSATIVA
LAPKPRLPARSLTRNSSTSSLSSLSSTSSTASRSAEVTKRTTRAQTRQSSTSSTSTSSSS
RSRRASTAHSTQVSLQSAAAKKAEVNRLQFSVTKKSIGRVTGTVKKRQAAR