Protein Info for mRNA_4475 in Rhodosporidium toruloides IFO0880

Name: 12843
Annotation: K05917 CYP51 sterol 14-demethylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 535 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 291 to 309 (19 residues), see Phobius details PF00067: p450" amino acids 44 to 378 (335 residues), 129 bits, see alignment E=1.2e-41 amino acids 403 to 528 (126 residues), 75.2 bits, see alignment E=2.4e-25

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (535 amino acids)

>mRNA_4475 K05917 CYP51 sterol 14-demethylase (Rhodosporidium toruloides IFO0880)
MGLLAHAGTAALALAGLFALAVALNVAWQLIAPRDPRRPPLVFHYVPVIGCAVSYGMDPL
GFLDECRRKYGPVFTYPLLGRKITATLGPLGSNFVLNGKLAHVNAEEAYTHLTTPVFGTE
VVYDVPNHVLMEQKKFVKFGLTTENFRRYVGLIRQEVLDYMSKHVYAEGTKTVSPGTDAF
ETSSEITILTASATLQGREVRAAMDKSFAQLYHDLDGGFTPLNFVFPKLPLPSYRRRDRA
QLKMREFYISILEKRRASTEEPDLDMLTALQNQEYKTGEPLTDKQIAHIMIALLMAGQHT
SAATGAWAILRLGENQDLQRRLYEEQLEYHLDKESGKLRPLEYETLSTPLLSAFIKELLR
MHPPLHSLMRKIILDCPVPASVGAPSAEPHASESFKKRNEGAEYVIPKGEYVLAAPGYSQ
VDEGIWGKDAKEFRAGRWLEEGNKVPGEEDEGEEDYGWGKISKGGKSAYLPFGAGRHRCI
GEQFANVQLGTIIATLVRENTWTLDQDFPGNDYTTMIVMPAKPRKVTFKRREKVL