Protein Info for mRNA_4530 in Rhodosporidium toruloides IFO0880

Name: 12898
Annotation: K00605 gcvT, AMT aminomethyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 431 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details TIGR00528: glycine cleavage system T protein" amino acids 31 to 422 (392 residues), 307.7 bits, see alignment E=5e-96 PF01571: GCV_T" amino acids 35 to 311 (277 residues), 248.4 bits, see alignment E=7.9e-78 PF08669: GCV_T_C" amino acids 340 to 421 (82 residues), 63.7 bits, see alignment E=1.2e-21

Best Hits

KEGG orthology group: K00605, aminomethyltransferase [EC: 2.1.2.10] (inferred from 55% identity to lbc:LACBIDRAFT_250466)

Predicted SEED Role

"Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10)" in subsystem Glycine and Serine Utilization or Glycine cleavage system or Photorespiration (oxidative C2 cycle) (EC 2.1.2.10)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.2.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (431 amino acids)

>mRNA_4530 K00605 gcvT, AMT aminomethyltransferase (Rhodosporidium toruloides IFO0880)
MLLPASARTAAPALARGLGRRAASSSAGTVKRTALNAFHRANGGKMVEFAGWDMPLSYEG
ADKSKCPGGPVAEHHQVRNSSGLFDVGHMIQSTFKGPGALAFLSHLLPASLATLPIPGED
AHRPFGSTLSVLLNEEGGILDDCMITRWGEDSFYLVTNAGRADVDIPWISKHVEQWNAEK
GEKVDFQVLESQALVALQGPKSHVALQRLLPSGLSVQKLLTFGQSLHLSIPSLSSSSTVH
IARGGYTGEDGFEISVPNAQAEDFAGMLLEQEEVKLAGLAARDSLRLEAGLCLYGHDLDE
SVGVGEAGLAWIVGKDRRTPGAFIGSERTLAELKKGGTTRKRVGLTVEKGAPAREGALIY
SSADAPTEPIGRITSGLPSPTIGQNIAMGYISTAEGLNKKGSEVFVEVRKKMRKAQVVGM
PWITPGYYRGE