Protein Info for mRNA_4604 in Rhodosporidium toruloides IFO0880

Name: 12972
Annotation: K10747 LIG1 DNA ligase 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 545 PF01068: DNA_ligase_A_M" amino acids 247 to 447 (201 residues), 38.9 bits, see alignment E=7.9e-14 PF14743: DNA_ligase_OB_2" amino acids 461 to 527 (67 residues), 96 bits, see alignment E=1.1e-31

Best Hits

Predicted SEED Role

"DNA ligase (ATP) (EC 6.5.1.1)" (EC 6.5.1.1)

Isozymes

Compare fitness of predicted isozymes for: 6.5.1.1

Use Curated BLAST to search for 6.5.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (545 amino acids)

>mRNA_4604 K10747 LIG1 DNA ligase 1 (Rhodosporidium toruloides IFO0880)
MAALTSSRSLVRHALPKLHPRIFNARPRFPPTPLARPLHHPFPSAPLSSTARLASQEDAE
SYPDQSEMFYEAIALHRLVHAKAITDKTPLTLGGAEHMDLPEPRTSLKLREEREVGSESS
SRSYKVKHFAPNAYLCTCLSWTMSRGRAVDVRSCKHLREILGDEHEDARCGPGVGVSKGS
RPRKKVVNLDGADSSAPSTSKKANTKASASNKAAASAKKASENAGEEAVPAAKKAKRERE
GGKEVLLAKSFDLETKKQDPTGWWISEKLDGVRAFWDGKALWSRVGYQFAAPDDFLAKLP
KEHELDGELFLGRNRFDETSGLVRRVNGVDWSQIRFMVFDIPSRGDEPFEKRQEFLLSLF
PPADPSTFSSSSAAAVNPTADETSATEVVEKEGDGIVRVLVQEKCEGWEHLMKRLEEVKN
VGGEGLMLRKPGSKYEPKRSSTLLKVKTFYDAEALVVDHEPGKGRFEGMLGSLVCVMEDR
KTQFKVGSGLNDERRVNPPPIGSIITYRFQELTQQKVPRFPTFVGERFDVAGPKDAVIAP
TTIGD