Protein Info for mRNA_4649 in Rhodosporidium toruloides IFO0880
Name: 13017
Annotation: K03934 NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 65% identical to NDUS1_NEUCR: NADH-ubiquinone oxidoreductase 78 kDa subunit, mitochondrial (nuo78) from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
KEGG orthology group: K03934, NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC: 1.6.5.3 1.6.99.3] (inferred from 71% identity to scm:SCHCODRAFT_68699)Predicted SEED Role
"NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)
MetaCyc Pathways
- aerobic respiration I (cytochrome c) (3/4 steps found)
- aerobic respiration III (alternative oxidase pathway) (2/3 steps found)
- NADH to cytochrome bd oxidase electron transfer I (1/2 steps found)
- NADH to cytochrome bo oxidase electron transfer I (1/2 steps found)
- Fe(II) oxidation (2/6 steps found)
- NAD(P)/NADPH interconversion (2/6 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.6.5.3, 1.6.99.3
Use Curated BLAST to search for 1.6.5.3 or 1.6.99.3
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (752 amino acids)
>mRNA_4649 K03934 NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1 (Rhodosporidium toruloides IFO0880) MLRLSRRIPASSRNPLALASSRAIHATSRASADVTLEIDGVPVTVPQGTALIQACEKAGA TIPRFCYHDRLNIAGNCRMCLVEVSPGPPKPQASCALPAMPGQKVKTNSPTVHKAREGVM EFLLANHPLDCPICDQGGECDLQDQSMRYGSDRTRFHEITGKRATEDKNFGPLIKTSMNR CIHCTRCVRFANEVAGVQDLGTSGRGNDMQIGTYIEKTINSEMSGNVIDLCPVGALTSKP YAFEARPWELKKTESVDVLDAVGSNIRVDSRGLVVMRVEPRLNDDINEEWISDKTRFAYD GLRTQRLNTPLVRVGDRFQPVTWQNALGAIKDGLASSGAKGNEIQAVAGSLADSESLVAL KDLVNRLGSDNTALDQPLGQAPPAHGVDHRAAYTFGSSIAGVEYADRVLLIGTNPRHEAA ILNARLRKTWLRNETDCALIGEQFDSTFGYDHLGADANAVRDVLSGKKGDWAKQLKEAKR PMIIVGSAVTEHEEGAKVFAEVAKFVEANKDKFVTPEWTGYNVLQRAASRTAAYDIGFVP SAAAGKTTPKFVYLLNADDFSPSSIPRDAFVVYQGHHGDVGAQYADVVLPGCAYTEKSVT WVNTEGRTQLGRAAVPPPGAAREDWKIIRALSEVLGETLPYDDTGALRDRMWDVSPTLVR YGELEKPSSVLEAVQALRKQGEREAGKRNGLGGRKGEFRKVFDSFYRTDPVSRNSVTMGQ CVKTFEQGIDGVEKPVIGDDGMAQAGHHPARA