Protein Info for mRNA_4770 in Rhodosporidium toruloides IFO0880

Name: 13138
Annotation: KOG0988 RNA-directed RNA polymerase QDE-1 required for posttranscriptional gene silencing and RNA interference

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1345 PF05183: RdRP" amino acids 196 to 950 (755 residues), 419 bits, see alignment E=1.9e-129

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1345 amino acids)

>mRNA_4770 KOG0988 RNA-directed RNA polymerase QDE-1 required for posttranscriptional gene silencing and RNA interference (Rhodosporidium toruloides IFO0880)
MAAPRTPSKTRHVDVLAPSAAPPRPIKALSPLRTSSTTSLLSPQAAKPVNIFAPVSKGPA
TGVGGATDDWRLENGRIVLVNAPSHLRMLAPCSWLHQYEHARYLHAGLSQSAVQWPCYPY
KIVDGVERNHLDEMSSYLAAALLPRRIKPYDRGLLVEVPQCESKKELEAAFKRGTILFSG
NLSIARDGKARPERLSVRLAPPSAGMGSALYRRFGSDRFFRLVLEDDLYRPFCWKDGTAV
YWAESGEGLETISLVDFAQRYLDVKLNGSMSVAKYAARFELGLTTTTPTVIFRRDQVFRT
PDINSDTLKLSFSAMTAICDEFRSKMPLDAQRLLPAPYIPSCIRGSVKPYAGAPSVEMVW
QLDYSTIDPPSSNAFIQLRPFEQGRTRPILKFQLVDKDGSFYSCIGPRSLKPVWVEGPPV
KKEEVVMTDGCSLISMGAMRVVAKKLAASGREAKVSAAAMPTVAQGRTGPGKGVWTLAPR
TPWNRWTAQSDHDIWIEVRDSQWKFKDRRTESFTFELHSLPSGKTGSKLGKRMFEVFAHC
GVPTTVFREMLKKQIDEIRRVLWDYPDLPTLLYHVQRQCNILEDRTSKARIASNPGSLKR
TNSNGPGGFDEDLDQVEEQQEQDVTSFVQDARLDPTSGAPNTVAEVVVEMLQSGFDPRQN
PHLADKLKRVEESLIRKQISFRIADDYSYTAFVVADHLGILEEGQFFFQLSERPLDANGL
QIGAVLGPALLTRSPAIQPCDIQKAATGVLCEAYAAYCDVIVVSTKGERLLCSILSGGDY
DGDKLVVMTNPELVAAFDSSKADPSFADPPFADSDWFEVDRRRVVDHVKPMIDLHNDAAL
AGVFMEGLHAGTQYGVLSVYHTTLAYTLGLDHPLTSEAGHLFCKALDGRKQGFSFSPEKW
KELKTKFFEPYKDKPRWTLCEDGKTAPNNVKYAKRPAEQGKHVMDELIREGEKAVDAAKM
SWSNRFDDLVYTVEGDLADPWTTAWESALNARHASPALFDDLCVILEHVKSIYAQYRQLF
SEWRRDRELRDRTECAAGAPGSPIKSPSKSKEWSGSSRNQKEALLQLSKRFWSLVVDNAF
ESAHLQGPAGAANVRVLMASCAYIEPLVPTFVPQANGVTLLRRLQDASPARPPAIAVTEA
LAVSTSSSEVTVLHAKEVTFSKAAASDDVEMEDSYGDDGLAWSQIPDDLTQVAVTSLGST
SSSQTATVVVSSSHPSNTTPTAPPSPAAAPRSPAKAPPAYSSYRARPFREVAGRSEIRFC
YDMAHRDVLALRADSLTRALHGDNPGATGIQAPKIAPHILDVLQVAKRCATLAQARTKVR
PRTLLEAKEWPPVSLGSPAKKARRN