Protein Info for mRNA_4896 in Rhodosporidium toruloides IFO0880

Name: 13264
Annotation: KOG0054 Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1370 transmembrane" amino acids 102 to 122 (21 residues), see Phobius details amino acids 157 to 179 (23 residues), see Phobius details amino acids 234 to 254 (21 residues), see Phobius details amino acids 260 to 280 (21 residues), see Phobius details amino acids 339 to 363 (25 residues), see Phobius details amino acids 377 to 401 (25 residues), see Phobius details amino acids 777 to 799 (23 residues), see Phobius details amino acids 823 to 848 (26 residues), see Phobius details amino acids 868 to 885 (18 residues), see Phobius details amino acids 905 to 933 (29 residues), see Phobius details amino acids 1011 to 1031 (21 residues), see Phobius details amino acids 1038 to 1058 (21 residues), see Phobius details PF00664: ABC_membrane" amino acids 116 to 390 (275 residues), 128.6 bits, see alignment E=7.5e-41 amino acids 783 to 1051 (269 residues), 140.9 bits, see alignment E=1.4e-44 PF00005: ABC_tran" amino acids 468 to 602 (135 residues), 74.7 bits, see alignment E=2.3e-24 amino acids 1121 to 1269 (149 residues), 108.3 bits, see alignment E=9e-35

Best Hits

Predicted SEED Role

"ATP-energized glutathione S-conjugate pump, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1370 amino acids)

>mRNA_4896 KOG0054 Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily (Rhodosporidium toruloides IFO0880)
MTWRDFVPFVESQGKIRLGEDEEQRRNGTAEDGEDWEQQDCPRLRANIFQRLTFSWMTPL
MKLGYRKFLTEEDLWALPEATFAVTPADGRKKKDSEKEKKPSLTGALISAYGGPFFVAAL
FKLGQDSLAFLQPWLLKRLLLFVASYNSVDGEPASHGYIIAVSMFFCAITQTILLHCYFS
RVFETGMRVRAGLISLIYKKALVLSPAERGGRLTGDIVNLQSTDSTRLQDLCTYGQIAWS
GVFQITLAFISLYSLLGWTMLVGVGVMVATMPLTAAIARYQTKLQRQQMKNKDQRTSIMS
EILNNIRSIKLYAWENSFAQRLFDVRNNKELRMLRKMGYLSAASNFLWSFSPFVVAFSSF
ATFSIITGKPLTSDIVFPAITLFQLLSFPLAVLPVVFSSLVEAYVSVDRITDFLVAKELQ
ASAVSVSVPRRELKSGDELVSIVQGDFTWSSLPAPDAPASTPQPENTLQDITLSVKKGEM
IAVVGRVGAGKSSLVSAILGEMNKVDGQVTVRGTVAYCAQQPWIMGGTVKQNITFGYRFD
PEFYELVLEACALKEDLKLLPQGDATEVGEKGISLSGGQKARVALARAVYSRADIYLLDD
PLSAVDAHVGRHLFDRVIGPTGLLRDRARLLCTNAIPYVEQADEVIMLRRGIVLERGTYA
SAIQGDTELSRLLIEFGKSGEDSGSESDETAAAENGSGDETAVESPKLDEAKLDAEDLTV
KLKIQNSKALAQRAEPIPVEEQKRATLIALKRSTRPKEKREQGSVKMAVYKEYIKANGYL
GAFLYIFTIVTQQALQIGTNVWLKHWSQHNSDTGDNGNVRYFLSIYFALGASASLVFFAN
GILLYSLCVIRSARLMHDRMFHSVMRSPMLFFEMTPIGTILNRFSRDIYVIDEVLARVFG
GFARTLAAVFGMVAVITTSAPAFLVVLAPLILVYRQVQKYYLATSRELKRLDATTKSPIF
ASFQETLGGLSTIRSYKQANRFVAENEARVDRNNETYFASVSCNRWLAIRLEFIGSCIIL
STATLAVFTLVRTSTVNAGLVGLMLSYALSTTQTLNWIVRSATEVETNIVSVERVQEYID
LKPEAALELPDRQPPADWPQHGTIRFDHVKARYRENLDLVLKDVSFEIKAGEKVGVCGRT
GAGKSSLTMVLYRIIEPEGGAVLIDGIDVGKIGLRDLRSRLSIIPQDSQMFAGKLRENLD
PTGQATDAQLWAALEQCRLKEHVERMEGKLDAHIDEGGTNFSAGQRQLICLGRALLRRSK
ILVLDEATAAVDVESDRDIQTVIRREFSTCTIFVIAHRLNTIMDCDKILVMSAGEVAEFD
SPANLLQQPDSIFRSLALEAGLAKSSGTNTPRTGGGKTPKSGAMTPARRD