Protein Info for mRNA_4988 in Rhodosporidium toruloides IFO0880

Name: 13356
Annotation: KOG1014 17 beta-hydroxysteroid dehydrogenase type 3, HSD17B3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 261 transmembrane" amino acids 7 to 25 (19 residues), see Phobius details PF00106: adh_short" amino acids 17 to 208 (192 residues), 70 bits, see alignment E=2e-23 PF13561: adh_short_C2" amino acids 19 to 242 (224 residues), 78.3 bits, see alignment E=7.1e-26

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

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Find the best match in UniProt

Protein Sequence (261 amino acids)

>mRNA_4988 KOG1014 17 beta-hydroxysteroid dehydrogenase type 3, HSD17B3 (Rhodosporidium toruloides IFO0880)
MAPSSNYILAVSGLGNVVGTGGSVARLFARELGYRVALISRPRKEVHDLKDEIAKGGGVA
EVFSVEEYSYQSMNKVFEDIKKHWPDGRLKCAVWNTSQWSRIPFLDITEKDITASATINI
ISATAFSQAAVRAFTSPSPGSDADQGGTLIMTGATSATRGHTHFGAFAAGKHGLRALSQS
IAREYGPQGVHVAFVIIDGTILTRITARMFSSVEGKDPNWMQDERQRLSPDSIARAYLYL
HQQTPDAWTLEMDLRPAKEKF