Protein Info for mRNA_5121 in Rhodosporidium toruloides IFO0880

Name: 13489
Annotation: K01137 GNS N-acetylglucosamine-6-sulfatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 575 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00884: Sulfatase" amino acids 39 to 422 (384 residues), 218.6 bits, see alignment E=2e-68 PF01663: Phosphodiest" amino acids 54 to 368 (315 residues), 24.9 bits, see alignment E=2.3e-09 PF16347: DUF4976" amino acids 425 to 539 (115 residues), 57.4 bits, see alignment E=2.4e-19

Best Hits

KEGG orthology group: None (inferred from 64% identity to aor:AOR_1_4194)

Predicted SEED Role

"Mucin-desulfating sulfatase MdsA precursor (EC 3.1.6.14)" (EC 3.1.6.14)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.6.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (575 amino acids)

>mRNA_5121 K01137 GNS N-acetylglucosamine-6-sulfatase (Rhodosporidium toruloides IFO0880)
MARDGRQQLPSLLLLLYARDPASPLLPLQHHPDSTMTRPNIIFIMADDHAAKAISAYGAG
INDTPGIDRLAKEGMRYDHCYVTNSICTPSRATILCGTHNHVNGVHTLDSKLDSNLPNVA
KHLRSSGYQTAMIGKWHLAGHGRLEKAHAPQGFDAWDILPGQGQYFDPMWINSSGPHREM
GYVTDITTDKAIDFIERRDKNRPFFAMVHHKAPHRPWECHPRHRELYKDEIRIPETYDDD
YKNRAKAASLAKMRVEADMSYQDLGLVQPEGGSELGELEIPFIDWFTSRKVPMPDDVSKI
RLIDKQTAEVFTFKTREELSKFKYQRYMQRYLRTIQSIDDGVGKLLDYLDMSGLAENTMV
IYTSDQGFFLGEHGWFDKRFIYEESFQMPFLIRWPSVIKPGSVSKDIISNVDFAATWLEA
AGLRIPNYMQGDSFLSSLKGVPRPADDKTVAYHRYWQHADPIHNAYAHYGIRNHRYKLIY
WYAESFDLPGTGKGGQEREWELFDCEKDPLELFNCWSDPSYAEVREEMVRLLNDKMETIG
DVPVHKVGVSGAELAEIDKAYEGAGISERAGEKNM